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CRYOPRESERVED CRYSTALS OF HEMOLIN, FASCICLIN III & HIGH PH NEONATAL FC RECEPTOR

CRYOPRESERVED CRYSTALS OF HEMOLIN, FASCICLIN III & HIGH PH NEONATAL FC RECEPTOR
冷冻保存的血红素晶体,FASCICLIN III
批准号:
6586735
负责人:
Pamela J Bjorkman
金额:
$14.32万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2002
资助国家:
美国
项目状态:
已结题
起止时间:
2002-03-01 至 2003-02-28

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中文摘要
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英文摘要
Proper function of a-lytic protease requires the presence of its N-terminal pro region, which catalyzes an as yet unidentified step in the folding of this enzyme. In order to better understand the folding mechanism, we are using x-ray crystallography to determine the structure of the pro region, both by itself and in a complex with folded protease. We have engineered several mutants containing cysteines to facilitate the preparation of heavy atom derivatives for multiple isomorphous replacement.
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Structural Characterization of Coronavirus Antibodies Raised by Infection and Vaccination
  • 批准号:
    10327994
  • 项目类别:
  • 资助金额:
    $150.76万
  • 财政年份:
    2022
  • 负责人:
    Pamela J Bjorkman
  • 依托单位:
CHEETAH Center for the Structural Biology of HIV Infection, Restriction, and Viral Dynamics
  • 批准号:
    10508317
  • 项目类别:
  • 资助金额:
    $116.03万
  • 财政年份:
    2022
  • 负责人:
    Pamela J Bjorkman
  • 依托单位:
Structural Characterization of Coronavirus Antibodies Raised by Infection and Vaccination
  • 批准号:
    10841242
  • 项目类别:
  • 资助金额:
    $97.15万
  • 财政年份:
    2022
  • 负责人:
    Pamela J Bjorkman
  • 依托单位:
CHEETAH Center for the Structural Biology of HIV Infection, Restriction, and Viral Dynamics
  • 批准号:
    10663363
  • 项目类别:
  • 资助金额:
    $170.74万
  • 财政年份:
    2022
  • 负责人:
    Pamela J Bjorkman
  • 依托单位:
海外基金