Sugar-sweetened Beverages and Weight Gain in Children

含糖饮料与儿童体重增加

• 批准号: 6576946
• 负责人: DAVID S LUDWIG
• 金额: $ 21.52万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2004-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6576946
• 关键词: adolescence (12-20); beverages; bioenergetics; body composition; caloric dietary content; clinical research; dietary carbohydrates; dietary restriction; eating; human subject; human therapy evaluation; interview; longitudinal human study; nutrition related tag; obesity; weight control

DESCRIPTION (provided by applicant): The prevalence of obesity has risen dramatically among children in the U.S. since the 1960s. Effective treatment of childhood obesity is widely recognized as instrumental to public health efforts to combat type 2 diabetes and heart disease. Many factors are thought to have contributed to the epidemic of pediatric obesity. One factor that has received increasing attention is consumption of sugar-sweetened beverages. Feeding studies suggest physiological mechanisms by which sugar in liquid form may be less satiating than other foods. One observational study found total energy consumption to be greater among children who consume sugar-sweetened beverages compared to non-consumes. Short-term interventional studies report increasing energy intake and body weight in subjects given sugar-sweetened beverages compared to non-caloric beverages. Our preliminary data found that the risk for becoming obese increased by about 60% in middle school children for every additional serving per day of sugar-sweetened beverage consumed. However, there are presently no longer-term intervention studies examining the effects of beverage consumption on body weight in children. The purpose of this project is to examine, in a pilot study; the effect of a home-based environmental intervention designed to decrease consumption of sugar-sweetened beverages among adolescents. Specifically, we plan to recruit subjects from a high school in Cambridge, Massachusetts who will be randomly assigned to experimental or control groups. The experimental group will receive weekly deliveries to their homes of a variety of non-caloric beverages for a period of 6 months. We anticipate that children in the experimental group will 1) decrease consumption of sugar-sweetened beverages; 2) decrease total energy consumption; 3) show improvements in various measure of diet quality; and 4) gain less weight than controls (change in BMI is the primary study endpoint). Because soft drinks are heavily advertised to children and widely available, this study and subsequent multi-center trials are necessary to determine whether public health efforts aimed at reducing consumption of sugar-sweetened beverages among children may be warranted.

描述（由申请人提供）： 自1960年代以来，美国儿童的肥胖症患病率急剧上升。对儿童肥胖症的有效治疗被广泛认为是对2型糖尿病和心脏病作斗争的公共卫生努力。人们认为许多因素有助于小儿肥胖的流行。受到越来越多的关注的一个因素是消耗糖饮料。喂养研究表明，与其他食物相比，液态糖的糖分可能较少的生理机制。一项观察性研究发现，与非货物相比，食用糖粉饮料的儿童的总能量更大。短期介入研究报告说，与非过滤饮料相比，给予糖饮料的受试者的能量摄入和体重增加。我们的初步数据发现，中学儿童的肥胖风险增加了约60％，每天食用每份糖甜饮料。但是，目前没有长期的干预研究检查饮料消耗对儿童体重的影响。该项目的目的是在一项试点研究中检查；基于家庭的环境干预措施的影响，旨在减少青少年中糖味饮料的消费。具体而言，我们计划从马萨诸塞州剑桥的一所高中招募受试者，他们将被随机分配到实验或对照组。实验组将在6个月的时间内每周收到各种非热门饮料的家园。我们预计实验组的儿童将1）减少糖甜饮料的消费； 2）减少总能耗； 3）在各种饮食质量方面表现出改善； 4）体重的增长少于对照（BMI的变化是主要的研究终点）。由于软饮料在儿童上广泛宣传并广泛可用，因此为确定旨在减少儿童中糖甜饮料消费的公共卫生努力是必要的。