Interactive Internet Interventions for smoking

描述(由调查员提供)：有重要的需要 有效、低成本的戒烟干预措施，可覆盖大范围 吸烟者人数。基于互联网的戒烟计划可以达到 越来越多的吸烟者。大约三分之一的人 是互联网用户；据估计，他们中有800万人吸烟。 基于互联网的戒烟计划可以是互动的、个性化的 基于参与者特征和兴趣的信息，提供较高的 选择的程度和灵活性，并提供来自双方同龄人的社会支持 和专业人士。虽然初始启动成本可能很高，但可以进行交互 互联网干预的维护成本很低，并提供24小时/7天服务 获得戒烟帮助。 我们将制定一个全面的互联网戒烟计划，包括三个 主要组件： (A)支持使用有效的药物疗法(例如， 尼古丁替代疗法和Zyban)，(B)认知-行为技能 发展；和(C)社会支持(主要通过在线论坛和聊天 房间)，并在随机对照试验中进行评估，该试验旨在评估 该计划的影响。控制条件将是运动和营养 专为互联网使用而设计的有效验证程序(PACE)。本节目 作为一种可靠的注意力安慰剂对照。 大约2000人将从大型工作地点登记，这些工作地点提供 内部网链接(和高带宽连接)到我们的网站。所有评估 将通过互联网和许多过程数据--使用 各种干预要素和讨论小组的记录-- 并自动存储。七天点患病率在三天和三天后停止 六个月的随访将作为主要结果，并辅以其他 患病率和持续戒烟结果。各种各样的学科特点 过程措施将作为预测者或调解者进行审查。之后 结果在六个月后进行评估，参与者将获得访问 条件截然不同，鼓励入学。二次分析将检查 PACE计划的有效性。拟议的设计将提供 关于低成本互联网有效性的重要实用信息 帮助吸烟者戒烟的干预措施。

DESCRIPTION (provided by investigator): There is an important need for validated, low-cost smoking cessation interventions that can reach large populations of smokers. Internet-based cessation programs can reach an increasingly large number of smokers. Approximately one third of all persons are Internet users; an estimated 8 million of them are cigarette smokers. Internet-based smoking cessation programs can be interactive, personalize information based on participant characteristics and interests, provide a high degree of choice and flexibility, and provide social support from both peers and professionals. While initial start-up costs can be high, interactive Internet interventions cost little to maintain, and provide 24-hour/7-day access to smoking cessation assistance. We will develop a comprehensive Internet smoking cessation program with three major components: (a) support for the use of efficacious pharmacological therapies (e.g., nicotine replacement therapy and Zyban), (b) a cognitive-behavioral skills development, and (c) social support (primarily via on-line forums and chat rooms), and evaluate it in a randomized control trial designed to assess the impact of the program. The control condition will be an exercise and nutrition program of proven efficacy (PACE+) designed for Internet use. This program serves as a credible attention-placebo control. Approximately 2000 persons will be enrolled from large worksites that provide intranet links (and high-bandwidth connections) to our website. All assessment will be accomplished via the Internet and much of the process data--use of various intervention elements and transcripts of discussion groups--is recorded and stored automatically. Seven-day point prevalence cessation at three- and six-month follow-ups will serve as the primary outcomes, augmented by other prevalence and sustained quit outcomes. A variety of subject characteristics and process measures will be examined as predictors or mediators. After outcomes are assessed at six months, participants will be given access to the contrasting condition and encouraged to enroll. Secondary analyses will examine the effectiveness of the PACE+ program. The proposed design will provide important practical information about effectiveness of a low-cost Internet intervention to assist smokers in stopping smoking.