BLOOD AND MARROW TRANSPLANT CLINICAL RESEARCH NETWORK

描述（由申请人提供）： 这项拨款申请的目的是成为一个核心的临床 血液和骨髓移植临床研究网络的中心。 弗雷德哈钦森癌症研究中心有很多特点 （FECRC）骨髓移植计划，使其成为一个有吸引力的候选人， 融入网络。首先，我们保持了一个大的，稳定的移植 几十年来，每年移植450至550名患者， 年，取得了良好的临床效果。因此，我们有机会获得一个相对 大量的病人。第二，我们的集团包括大量的 研究人员集中在移植的一般主题上。这一群体 得到了7个P0ls和23个R0ls的支持，去年发表了142篇关于 话题因此，我们的列入将有助于确保可能的研究来源， 在移植网络中的未来测试。第三，我们的计划深入 致力于临床合作研究。例如，去年451个中的231个 在西雅图移植的患者（51%）进入多机构 审判最后，FHCRC提供了一个出色的环境， 进行所描述的各种研究，采用最先进的临床和 实验室设施。血液和骨髓移植临床 研究网络有可能促进研究， 移植结果的显著改善。列入 弗雷德哈钦森癌症研究中心在这个网络应该帮助它实现 这个目标

DESCRIPTION (provided by applicant): The objective of this grant application is to become one of the core clinical centers in the proposed Blood and Marrow Transplant Clinical Research Network. There are a number of features of the Fred Hutchinson Cancer Research Center (FECRC) Marrow Transplant Program that make it an attractive candidate for inclusion in the Network. First, we have maintained a large, stable transplant program for several decades transplanting between 450 and 550 patients per year with excellent clinical outcomes. Thus, we have access to a relatively large number of patients. Second, our group includes a large number of investigators focused on the general topic of transplantation. This group is supported by seven P0ls and 23 R0ls, and last year published 142 papers on the topic. Thus, our inclusion will help assure a source of possible studies for future testing in the Transplant Network. Third, our program is deeply committed to cooperative clinical research. For example, last year 231 of 451 patients transplanted in Seattle (51%) were entered onto multi-institutional trials. Finally, the FHCRC provides an outstanding environment in which to conduct the sorts of studies described, with state-of-the-art clinical and laboratory facilities. The proposed Blood and Marrow Transplant Clinical Research Network has the potential to facilitate studies leading to substantial improvements in the outcome of transplantation. Inclusion of the Fred Hutchinson Cancer Research Center in this network should help it achieve this goal.