Hutchinson Center as Lead Academic Participating Site (U10)

描述（由申请人提供）：NCI国家临床试验网络（NCTN）的目标是开发和开展最先进的癌症治疗和先进的影像学临床试验，特别是大型、明确的多机构试验，评估新的癌症治疗和相关的临床方法。NCTN领导学术参与站点（LAPS）是该网络的一个组成部分，将与一个或多个成人网络组联合，在NCTN临床试验的开发和实施中提供科学领导，并为整个NTCN进行的临床试验提供大量累积。Fred Hutchinson癌症研究中心（FHCRC）是美国领先的癌症研究中心之一，也是唯一一家nci指定的综合性癌症研究中心，服务于WWAMI（华盛顿，怀俄明，阿拉斯加，蒙大拿州和爱达荷州）地区。FHCRC广泛而深入的临床前和临床研究项目将以三种主要方式支持NCTN项目：(1)FHCRC成员的科学专业知识将通过他们在NCI和SWOG， NRG和ACRIN的直接活动继续为NCTN项目的领导做出贡献。(2) FHCRC的创新临床前和临床研究将为形成下一代合作组试验提供必要的初步信息。(3) FHCRC庞大的患者基础，加上专家临床医生和临床试验基础设施，将确保NCTN试验的大量积累。Fred Hutchinson癌症研究中心及其合作伙伴致力于实现国家临床试验网络（NCTN）的目标，并将努力为我们国家的临床试验网络提供领导。

DESCRIPTION (provided by applicant): The goal of the NCI National Clinical Trials Network (NCTN) is to develop and conduct state-of-the-art cancer treatment and advanced imaging clinical trials, especially large, definitive multi-institutional trials evaluating new cancer therpies and related clinical approaches. NCTN Lead Academic Participating Sites (LAPS) are one component of this network and will provide scientific leadership in the development and conduct of NCTN clinical trials in association with one or more adult Network Groups as well as substantial accrual to clinical trials conducted across the entire NTCN. The Fred Hutchinson Cancer Research Center (FHCRC) is among the nation's leading cancer centers and is the only NCI-designated comprehensive cancer research center serving the WWAMI (Washington, Wyoming, Alaska, Montana and Idaho) region. The broad and deep pre-clinical and clinical research programs at the FHCRC will support the NCTN Program in three major ways: (1) The scientific expertise of the members of the FHCRC will continue to contribute to the leadership of the NCTN program through their activities directly at the NCI and in SWOG, NRG and ACRIN. (2) The innovative pre-clinical and clinical research studies at the FHCRC will provide the preliminary information necessary to shape the next generation of cooperative group trials. (3) The large patient base at the FHCRC combined with expert clinicians and clinical trials infrastructure will assure substantial accrual to NCTN trials. Fred Hutchinson Cancer Research Center and its partners are committed to the goals of the National Clinical Trials Network (NCTN) and will work to provide leadership for our nation's clinical trials network.