Hutchinson Center as Lead Academic Participating Site (U10)

描述(由申请人提供)：NCI国家临床试验网络(NCTN)的目标是开发和进行最先进的癌症治疗和先进的成像临床试验，特别是评估新的癌症疗法和相关临床方法的大型、决定性的多机构试验。NCTN领先学术参与网站(LAPS)是这个网络的一个组成部分，将在与一个或多个成人网络小组合作开发和实施NCTN临床试验方面提供科学领导，并为整个NTCN进行的临床试验带来可观的收益。弗雷德·哈钦森癌症研究中心(FHCRC)是美国领先的癌症研究中心之一，也是NCI指定的唯一为WWAMI(华盛顿州、怀俄明州、阿拉斯加州、蒙大拿州和爱达荷州)地区服务的综合性癌症研究中心。FHCRC广泛而深入的临床前和临床研究计划将以三种主要方式支持NCTN计划：(1)FHCRC成员的科学专业知识将继续通过他们在NCI以及SWOG、NRG和ACRIN的活动为NCTN计划的领导做出贡献。(2)FHCRC的创新临床前和临床研究研究将提供形成下一代合作团体试验所需的初步信息。(3)FHCRC庞大的患者基础与专家临床医生和临床试验基础设施相结合，将确保NCTN试验的可观收益。弗雷德·哈钦森癌症研究中心及其合作伙伴致力于国家临床试验网络(NCTN)的目标，并将努力为我国的临床试验网络提供领导。

DESCRIPTION (provided by applicant): The goal of the NCI National Clinical Trials Network (NCTN) is to develop and conduct state-of-the-art cancer treatment and advanced imaging clinical trials, especially large, definitive multi-institutional trials evaluating new cancer therpies and related clinical approaches. NCTN Lead Academic Participating Sites (LAPS) are one component of this network and will provide scientific leadership in the development and conduct of NCTN clinical trials in association with one or more adult Network Groups as well as substantial accrual to clinical trials conducted across the entire NTCN. The Fred Hutchinson Cancer Research Center (FHCRC) is among the nation's leading cancer centers and is the only NCI-designated comprehensive cancer research center serving the WWAMI (Washington, Wyoming, Alaska, Montana and Idaho) region. The broad and deep pre-clinical and clinical research programs at the FHCRC will support the NCTN Program in three major ways: (1) The scientific expertise of the members of the FHCRC will continue to contribute to the leadership of the NCTN program through their activities directly at the NCI and in SWOG, NRG and ACRIN. (2) The innovative pre-clinical and clinical research studies at the FHCRC will provide the preliminary information necessary to shape the next generation of cooperative group trials. (3) The large patient base at the FHCRC combined with expert clinicians and clinical trials infrastructure will assure substantial accrual to NCTN trials. Fred Hutchinson Cancer Research Center and its partners are committed to the goals of the National Clinical Trials Network (NCTN) and will work to provide leadership for our nation's clinical trials network.