SCORE PROGRAM AT NEW MEXICO STATE UNIVERSITY, LAS CRUCES

这是位于拉斯克鲁塞斯的新墨西哥州立大学(NMSU)一个新的SCORE项目的申请表。NMSU的一个目标是扩大该机构的研究，让希望从事生物医学科学学科事业的少数民族学生参与其中。拟议的SCORE计划有其目标：(I)通过增加进行生物医学研究的教员人数，增加专门的单用户研究仪器的库存，并提高维护研究仪器的能力，显著提高NMSU进行生物医学相关研究的能力；(Ii)通过扩大教员的资助努力，增加研究出版物的数量和质量，显著提高NMSU进行的生物医学研究的数量和质量；(Iii)将SCORE计划的活动与预期的Rise计划相结合，通过邀请学生参与SCORE计划的研究项目，最大限度地利用资源培训少数族裔科学家从事生物医学科学；(4)通过聘请训练有素的人员参与成绩方案的评估计划，并由外部评估委员会对该方案进行年度审查，提高NMSU自我评估、评估和监测其多组成部分研究方案的能力。本申请书包含19个研究子项目和3个试验子项目的研究建议。这些建议中代表的学科包括农学、动物学、人类学、生物化学、生物学、化学、化学工程、分子生物学、微生物学和心理学。建议项目的研究课题包括：医疗诊断试剂的同位素标记方法；禽类心血管适应性；细菌蛋白小体；CHO细胞中的糖基化过程；细胞凋亡；E.ColiO157：H7的耐酸性；次级代谢的代谢工程；RNA病毒的进化；胞质和叶绿体谷氨酰胺合成酶；生物脱氯反应；环境胁迫抗性的机制；苦马豆碱的毒代动力学；生长激素的神经调节；皮质醇和行为发育的同步性；血压的胚胎控制；用于分解外消旋混合物的粘土的修饰；内耳发育过程中的基因表达；阳离子螯合剂、类固醇和乙二醇类衍生物的化学合成；以及硼化生物分子。该计分计划将延续已有24年历史的MBRS计划，自1974年以来，该计划已使280名少数族裔学生(83%的参与者)进入学士学位后课程，并产生了52名少数族裔博士学位获得者。

This is an application for a new SCORE Program at New Mexico State University (NMSU) at Las Cruces. A goal of NMSU is to expand research is at the institution for participation by ethnic minority students who desire to pursue careers in the biomedical science disciplines. The proposed SCORE Program has its goals: (i) To significantly improve the capabilities of NMSU to conduct biomedically relevant research by increasing the numbers of faculty who conduct biomedical research, increasing the inventory of specialized single-user research instrumentation, and improving the capacity to maintain research instrumentation; (ii) To significantly improve the quantity and quality of biomedical research conducted at NMSU by broadening grantsmanship efforts of faculty participants and increasing the numbers and quality of research publications; (iii) To integrate the activities of the SCORE Program with an anticipated RISE Program to maximize resources for training minority scientists in the biomedical sciences by engaging students in SCORE Program research projects; (iv) To increase the capacity of NMSU to self-evaluate, assess, and monitor its multi- component research programs by engaging trained personnel in the SCORE Program's evaluation plan and subjecting the Program to annual review by an external evaluation committee. This application contains research proposals for nineteen research subprojects and three pilot subprojects. Disciplines represented among these proposals include Agronomy, Animal Science, Anthropology, Biochemistry, Biology, Chemistry, Chemical Engineering, Molecular Biology, Microbiology and Psychology. The research topics of proposed projects include methods for radiolabeling medical diagnostic reagents with technetium and rhenium, avian cardiovascular adaptations, the bacterial proteosome, glycosylation processes in CHO cells, apoptosis, acid tolerance of E. coli O157:h7, metabolic engineering of secondary metabolism, evolution of RNA viruses, cytosolic and chloroplastic glutamine synthase, biological dechlorination reactions, mechanisms of environmental stress resistance, toxicokinetics of swainonine, neuromodulation of growth hormone, maternal/infant synchrony in cortisol and behavior development, embryonic control of blood pressure, modification of clays for resolving racemic mixtures, gene expressions during inner ear development, and chemical synthesis of cation chelators, steroids and etoposide derivatives, and boronated biomolecules. This SCORE Program will continue a 24-year old MBRS Program which has advanced 280 minority students (83% of participants) on to post baccalaureate programs and produced 52 minority Ph.D. recipients since 1974.