Cerebral Vascular Biology 2003 Conference

描述(由申请人提供)： 这项提案是为支持2003年脑血管生物学大会(CVB 2003)募集资金，这是一次来自世界各地的研究人员参加的会议，他们对神经微环境的血管控制以及脑血管系统在脑瘤、神经退行性疾病、中风、缺血和神经感染等疾病过程中的作用感兴趣。由于脑血管系统阻碍了许多药物的中枢神经系统药物传递，因此会议的一个必然焦点将是开发新的治疗策略，以改善药物传递以治疗中枢神经系统疾病。CVB2003将于2003年6月在得克萨斯州阿马里洛举行，这将是过去十年来在明尼苏达州德卢斯、法国巴黎、俄勒冈州波特兰和英国剑桥举行的一系列CVB会议中的第四次。这次会议将汇集来自世界各地多个不同领域的科学家，他们对大脑毛细血管内皮细胞以及血-脑和血-脑脊液屏障感兴趣。尽管脑血管领域的科学家有机会在国家会议和会议上介绍和交流他们的研究，但很少有这样的会议集中关注血脑屏障及其在中枢神经系统疾病的医学治疗中出现的问题。第一次CVB会议是在20世纪90年代初举行的，目的是促进来自世界各地的科学家在这一关键领域的交流，并帮助建立研究互动。血脑屏障对制药业特别重要，因为血脑屏障是中枢神经系统药物开发的主要障碍。CVB2003将重点介绍大脑毛细血管内皮细胞的调节和功能领域的新进展，以及“克服”血脑屏障给药的新战略发展。特邀演讲者是根据最近对该领域的前沿贡献(例如突破性进展和见解)以及他们的演讲技能来选择的。为争取来自不同地理区域和该领域内感兴趣的专题的发言者作出了巨大努力。会议主席是根据他们在外地的显赫地位和经验挑选出来的。会议将为新老研究人员以及血脑屏障领域的学生和博士后提供重要的口头和海报演示机会，以分享想法和促进新的合作。

DESCRIPTION (provided by applicant): This proposal is a request for funds to support Cerebral Vascular Biology 2003 (CVB 2003), a meeting of researchers from across the world who are interested in vascular control of the neural microenvironment and the role of brain vasculature in disease processes including brain tumors, neurodegenerative disorders, stroke, ischemia, and neural infections. Because the brain vasculature impedes CNS drug delivery for many agents, a corollary focus of the meeting will be the development of novel therapeutic strategies to improve drug delivery to treat CNS disorders. CVB2003 will be held in June 2003 in Amarillo, Texas and will be the fourth in a series of CVB meetings that have been held previously over the past decade in Duluth, Minnesota, Paris, France, Portland Oregon, and Cambridge, England. The meeting will bring together scientists from a number of diverse fields from across the world who have interests in the brain capillary endothelium, and the blood-brain and blood-CSF barriers. Although opportunities exist at national meetings and conferences for scientists in the cerebrovascular field to present and communicate their research, few such meetings provide a concentrated focus on the blood-brain barrier and the problems that it presents in medical therapy of CNS disorders. The first CVB meeting was held in the early 1990's to help foster communication among scientists in the field from across the world in this key area and to help build research interaction. The blood-brain barrier is of particular interest to the pharmaceutical industry as the barrier is a major impediment to drug development for the CNS. CVB2003 will focus on new advances in areas of regulation and function of the brain capillary endothelium as well as novel developments in strategies to "overcome" the blood-brain barrier to drug delivery. Invited speakers have been chosen based upon recent cutting-edge contributions to the field (e.g., breakthrough advances and insights) as well as their presentation skills. A strong effort was made to obtain speakers from diverse geographical areas and interest topics within the field. Session chairs were chosen based upon their eminence and experience within the field. The meeting will provide critical oral and poster presentation opportunities for new and established researchers as well as students and post-docs within the blood-brain barrier area to share ideas and foster new collaborations.