Cognitive-behavioral Treatment of Anxiety/ Primary Care

描述(由候选人提供)：这项以患者为导向的研究职业发展奖(K23)将使Weisberg博士能够在为焦虑症患者开发和评估干预计划方面开始一系列计划研究。她的重点将是为患有焦虑症的初级保健患者开发一种认知行为团体疗法。焦虑症非常普遍，而且危害很大。寻求焦虑症帮助的人更有可能在初级保健中被看到，而不是在精神健康环境中，而且这些患者中的大多数没有得到适当的治疗。Weisberg博士的培训目标包括：(1)扩大她在治疗开发方面的知识和经验，重点是开发和评估医疗环境中的焦虑症治疗；(2)获得在初级保健环境中进行干预的专业知识；(3)扩大她对治疗结果研究进行的理解；以及(4)进一步发展她的统计技能，特别是与干预/临床试验研究相关的技术。这些培训目标将通过(1)布朗医学院可用的资源；(2)马丁·凯勒博士、米歇尔·克拉斯克博士、凯·迪克森博士提供的高质量指导以及汇集的顾问团队(大卫·巴洛博士、查尔斯·伊顿博士和罗伯特·斯托特博士)的专业知识；(3)专注于课程、培训和临床经验；以及(4)拟议的研究项目来实现。拟议的研究计划包括为患有惊恐障碍、广泛性焦虑障碍和/或社交焦虑障碍的初级保健患者开发和经验性测试一种新的治疗方法。新的治疗方法，学习在初级保健中缓解焦虑(LEAP)将纳入CBT治疗特定焦虑症(即认知重组和暴露)的通用方法，并适用于有一系列焦虑症诊断的初级保健患者。具体的研究目标是：(1)制定LEAP疗法、其手册、治疗师培训程序和治疗保真度措施，以及(2)进行随机对照试点研究，将LEAP与常规治疗进行比较，以评估拟议治疗的可行性和可接受性，并获得治疗效果大小，以支持在未来更大规模的试验中对该方案进行检查。

DESCRIPTION (provided by candidate): This Mentored Patient-Oriented Research Career Development Award (K23) will enable Dr. Weisberg to begin a programmatic line of research in the development and evaluation of intervention programs for medical patients with anxiety disorders. Her emphasis will be on developing a cognitive behavioral group treatment for primary care patients with anxiety disorders. Anxiety disorders are highly prevalent and impairing. Individuals seeking help for anxiety are more likely to be seen in primary care than in mental health settings, and the majority of these patients do not receive adequate treatment. Dr. Weisberg's training goals include: (1) broadening her knowledge and experience in treatment development, with a focus on developing and evaluating treatments for anxiety disorders in medical settings; (2) acquiring expertise in conducting interventions in primary care settings; (3) expanding her understanding of the conduct of treatment outcome studies; and (4) further developing her statistical skills, with particular emphasis on techniques relevant to intervention / clinical trials research. These training goals will be achieved through (1) the resources available at Brown Medical School; (2) the high quality mentorship provided by Drs. Martin Keller, Michelle Craske, Kay Dickersin, and the expertise of the assembled consultant team (Drs. David Barlow, Charles Eaton, and Robert Stout); (3) focused coursework, training, and clinical experiences; and (4) the proposed research project. The proposed research plan involves developing and empirically testing a new treatment for primary care patients with panic disorder, generalized anxiety disorder, and/or social anxiety disorder. The new treatment, Learning to Ease Anxiety in Primary care (LEAP) will incorporate methods universal to CBT for specific anxiety disorders (i.e., cognitive restructuring and exposure) and adapted for primary care patients with a range of anxiety diagnoses. The specific research aims are to: (1) develop the LEAP treatment, its manual, therapist training procedures, and treatment fidelity measures and (2) conduct a randomized, controlled pilot study comparing LEAP to treatment as usual, in order to evaluate the feasibility and acceptability of the proposed treatment, and obtain a treatment effect size to support an examination of the protocol in a future, larger trial.