Cognitive-behavioral Treatment of Anxiety/ Primary Care

描述（由候选人提供）：这项以患者为导向的指导研究职业发展奖（K23）将使Weisberg博士能够开始对患有焦虑症的医疗患者的干预方案的开发和评估进行规划性的研究。她的重点将是开发一种认知行为群体治疗焦虑症的初级保健患者。焦虑症是非常普遍和有害的。因焦虑而寻求帮助的人更有可能在初级保健机构就诊，而不是在精神卫生机构，这些患者中的大多数没有得到充分的治疗。Weisberg博士的培训目标包括：(1)拓宽她在治疗开发方面的知识和经验，重点是在医疗环境中开发和评估焦虑症的治疗方法；(2)获得在初级保健机构进行干预的专业知识；(3)拓展她对治疗结果研究的理解；(4)进一步发展她的统计技能，特别强调与干预/临床试验研究相关的技术。这些培训目标将通过(1)布朗医学院的资源来实现；(2)博士的高质量指导。Martin Keller, Michelle Craske, Kay Dickersin，以及集结的顾问团队的专业知识(dr。大卫·巴洛、查尔斯·伊顿和罗伯特·斯托特)；(3)有针对性的课程、培训和临床经验；(4)拟研究课题。拟议的研究计划包括开发和实证测试一种新的治疗惊恐障碍、广泛性焦虑障碍和/或社交焦虑障碍的初级保健患者的方法。新的治疗方法，学习缓解初级保健中的焦虑（LEAP）将结合CBT对特定焦虑症（即认知重构和暴露）的通用方法，并适用于具有一系列焦虑诊断的初级保健患者。具体的研究目标是：(1)制定LEAP治疗、其手册、治疗师培训程序和治疗保真度措施；(2)进行一项随机、对照的试点研究，将LEAP与常规治疗进行比较，以评估拟议治疗的可行性和可接受性，并获得治疗效应大小，以支持在未来更大规模的试验中对该方案的审查。

DESCRIPTION (provided by candidate): This Mentored Patient-Oriented Research Career Development Award (K23) will enable Dr. Weisberg to begin a programmatic line of research in the development and evaluation of intervention programs for medical patients with anxiety disorders. Her emphasis will be on developing a cognitive behavioral group treatment for primary care patients with anxiety disorders. Anxiety disorders are highly prevalent and impairing. Individuals seeking help for anxiety are more likely to be seen in primary care than in mental health settings, and the majority of these patients do not receive adequate treatment. Dr. Weisberg's training goals include: (1) broadening her knowledge and experience in treatment development, with a focus on developing and evaluating treatments for anxiety disorders in medical settings; (2) acquiring expertise in conducting interventions in primary care settings; (3) expanding her understanding of the conduct of treatment outcome studies; and (4) further developing her statistical skills, with particular emphasis on techniques relevant to intervention / clinical trials research. These training goals will be achieved through (1) the resources available at Brown Medical School; (2) the high quality mentorship provided by Drs. Martin Keller, Michelle Craske, Kay Dickersin, and the expertise of the assembled consultant team (Drs. David Barlow, Charles Eaton, and Robert Stout); (3) focused coursework, training, and clinical experiences; and (4) the proposed research project. The proposed research plan involves developing and empirically testing a new treatment for primary care patients with panic disorder, generalized anxiety disorder, and/or social anxiety disorder. The new treatment, Learning to Ease Anxiety in Primary care (LEAP) will incorporate methods universal to CBT for specific anxiety disorders (i.e., cognitive restructuring and exposure) and adapted for primary care patients with a range of anxiety diagnoses. The specific research aims are to: (1) develop the LEAP treatment, its manual, therapist training procedures, and treatment fidelity measures and (2) conduct a randomized, controlled pilot study comparing LEAP to treatment as usual, in order to evaluate the feasibility and acceptability of the proposed treatment, and obtain a treatment effect size to support an examination of the protocol in a future, larger trial.