Cognitive-behavioral Treatment of Anxiety/ Primary Care

描述（由候选人提供）：这个指导以患者为导向的研究职业发展奖（K23）将使博士Weisberg开始在开发和评估焦虑症患者的干预方案的研究方案线。她的重点将是为患有焦虑症的初级保健患者开发认知行为小组治疗。焦虑症是非常普遍和有害的。因焦虑寻求帮助的人更有可能在初级保健中而不是在心理健康环境中看到，这些患者中的大多数没有得到充分的治疗。Weisberg博士的培训目标包括：（1）扩大她在治疗开发方面的知识和经验，重点是在医疗环境中开发和评估焦虑症的治疗方法;（2）获得在初级保健环境中进行干预的专业知识;（3）扩大她对治疗结果研究的理解;及（4）进一步发展她的统计技能，特别强调与干预/临床试验研究有关的技术。这些培训目标将通过以下方式实现：（1）布朗医学院提供的资源;（2）Martin Keller、Michelle Craske、Kay Dickersin博士提供的高质量指导，以及顾问团队（大卫巴洛、查尔斯伊顿和罗伯特斯托特博士）的专业知识;（3）重点课程、培训和临床经验;以及（4）拟议的研究项目。拟议的研究计划涉及开发和经验测试一种新的治疗方法，用于治疗惊恐障碍、广泛性焦虑障碍和/或社交焦虑障碍的初级保健患者。新的治疗方法，学习缓解焦虑的初级保健（LEAP）将纳入通用的方法CBT的特定焦虑症（即，认知重建和暴露），并适用于具有一系列焦虑诊断的初级保健患者。具体的研究目标是：（1）开发LEAP治疗，其手册，治疗师培训程序和治疗保真度措施，（2）进行随机对照试点研究，比较LEAP与常规治疗，以评估拟议治疗的可行性和可接受性，并获得治疗效果大小，以支持在未来更大的试验中检查方案。

DESCRIPTION (provided by candidate): This Mentored Patient-Oriented Research Career Development Award (K23) will enable Dr. Weisberg to begin a programmatic line of research in the development and evaluation of intervention programs for medical patients with anxiety disorders. Her emphasis will be on developing a cognitive behavioral group treatment for primary care patients with anxiety disorders. Anxiety disorders are highly prevalent and impairing. Individuals seeking help for anxiety are more likely to be seen in primary care than in mental health settings, and the majority of these patients do not receive adequate treatment. Dr. Weisberg's training goals include: (1) broadening her knowledge and experience in treatment development, with a focus on developing and evaluating treatments for anxiety disorders in medical settings; (2) acquiring expertise in conducting interventions in primary care settings; (3) expanding her understanding of the conduct of treatment outcome studies; and (4) further developing her statistical skills, with particular emphasis on techniques relevant to intervention / clinical trials research. These training goals will be achieved through (1) the resources available at Brown Medical School; (2) the high quality mentorship provided by Drs. Martin Keller, Michelle Craske, Kay Dickersin, and the expertise of the assembled consultant team (Drs. David Barlow, Charles Eaton, and Robert Stout); (3) focused coursework, training, and clinical experiences; and (4) the proposed research project. The proposed research plan involves developing and empirically testing a new treatment for primary care patients with panic disorder, generalized anxiety disorder, and/or social anxiety disorder. The new treatment, Learning to Ease Anxiety in Primary care (LEAP) will incorporate methods universal to CBT for specific anxiety disorders (i.e., cognitive restructuring and exposure) and adapted for primary care patients with a range of anxiety diagnoses. The specific research aims are to: (1) develop the LEAP treatment, its manual, therapist training procedures, and treatment fidelity measures and (2) conduct a randomized, controlled pilot study comparing LEAP to treatment as usual, in order to evaluate the feasibility and acceptability of the proposed treatment, and obtain a treatment effect size to support an examination of the protocol in a future, larger trial.