Research in Infectious Diseases

描述（由申请人提供）：该计划的主要目的是培养医生在生物医学研究的职业生涯。过去，我们专注于培训医生进行实验室研究，但最近我们已经开始培训医生进行实验室或面向患者的研究（重点是转化临床研究）。我们每年接受1-2名医生，他们将接受三年的培训（共6个职位）。医生将在完成内科或儿科住院医师培训后进入此培训计划。该计划还将培养少量博士。博士后研究员从事传染病研究，重点是微生物发病机制。通过混合医学博士和博士同一项目的博士后研究员，我们增强了这两个群体的教育体验。博士科学家一般会在获得学位后立即进入我们的项目，但有些人可能已经接受了一年或多年的博士后培训。将鼓励所有接受实验室研究培训的医生在培训补助金支持的期限之后继续接受2-3年的培训。我们使用大学医院，VA医学中心和抗病毒研究中心（AVRC）进行临床研究培训，并使用以下教师的研究实验室进行实验室研究培训。实验室研究员将参加由加州大学圣地亚哥分校生物系教授的适当课程。如果合适，我们将允许研究员在其他UCSD教师的实验室进行培训。进入临床研究轨道的研究员也将有机会在适当的研究实验室工作，学习特定的技术。所有从事以患者为导向的研究的研究员都将参加NIH支持的通过补充培训增强临床研究（CREST）课程。他们还将能够报名参加圣地亚哥州立大学公共卫生学院的课程，并有机会获得公共卫生硕士学位。约书亚菲勒尔博士将负责培训的总体方向，艾伦麦卡琴博士将负责以患者为导向的研究部分。斯蒂芬·斯佩克特博士将监督儿科研究医生。

DESCRIPTION (provided by applicant): This program's primary purpose is to train physicians for careers in biomedical research. In the past we focused on training physicians to do laboratory research, but recently we have begun to train physicians to do either laboratory or patient-oriented research (with an emphasis on translational clinical research). We accept 1-2 physicians/year and they will train for three years (a total of 6 positions). Physicians will enter this training program after they have completed residency training in either Internal Medicine or Pediatrics. The program will also train a small number of Ph.D. postdoctoral fellows to do research on infectious diseases, with an emphasis on microbial pathogenesis. By mixing M.D. and Ph.D. postdoctoral fellows in the same program, we enhance the educational experience of both groups. Ph.D. scientists will generally enter our program immediately after they earn their degrees, but some may have had one or more years of postdoctoral training. All physicians who train to do laboratory research will be encouraged to continue their training for another 2-3 years beyond the period supported by the training grant. We use University Hospital, the VA Medical Center, and the Antiviral Research Center (AVRC) for clinical research training, and the research laboratories of the faculty members listed below for the laboratory research training. Laboratory research fellows will enroll in appropriate courses taught by the Biology Department at UC San Diego. We will allow fellows to train in laboratories of other UCSD faculty if appropriate. Fellows entering the clinical research track also will have the opportunity to work in appropriate research laboratories to learn specific techniques. All fellows doing patient-oriented research will enroll in the NIH-supported Clinical Research Enhancement through Supplemental Training (CREST) course. They will also be able to enroll in courses at the School of Public Health at San Diego State University and have the opportunity to obtain an MPH degree. Dr. Joshua Fierer will be responsible for the overall direction of training, and Dr. Allen McCutchan will be responsible for the patient-oriented research component. Dr. Stephen Spector will supervise the Pediatric research physicians.