INTERPERSONAL PSYCHOTHERAPY FOR ANTENATAL DEPRESSION

描述（改编自申请人的摘要）： 一项拟议的研究是评估人际心理治疗的疗效 (IPT)来治疗产前抑郁症治疗结果是 在这项研究中调查包括IPT对减少的影响， 女性的抑郁症状和抑郁缓解率。 治疗引起的社会和婚姻适应的变化也将 被评价。本研究的第二个目的是确定 与IPT的反应相关，因此可能受益于 将来可以更准确地识别IPT。第三个目标 拟议的研究是评估治疗与IPT期间的效果 妊娠对妇女产后抑郁症状的影响。第四个目标 研究的目的是确定与高血压相关的因素。 接受IPT或IPT的妇女产后抑郁症的水平 或对照治疗。 共有110名妇女在怀孕的第一和第二个三个月将 从爱荷华州的孕产妇健康中心（MHC）招募。这 招聘战略将包括来自各种社会经济部门的妇女， 班级以及农村和城市环境。女性将被随机分配到 IPT治疗或常规治疗。接受治疗的妇女 通常情况下，将在当地MHC接受医生的治疗。 常规治疗旨在反映以下治疗： 妇女目前在社区接受产前抑郁症治疗， 对IPT的有效性进行有效测试。IPT将在12个月内交付 在接受IPT的组中，在产前期间对妇女进行为期10周的检查。 在治疗前、治疗期间和治疗结束后对女性进行评估， 以评估其有效性。女性也将被跟踪一个 产后一年评估其产后情绪和社会 加强结构性改革 我们预计，接受IPT治疗的女性， 抑郁症和更高的社会功能水平比妇女在控制 条件我们还预计，接受IPT的妇女将有显着的 产褥期的抑郁症发病率低于 控制条件。我们假设IPT将是一种有效的低风险 在怀孕期间使用药物的替代品。

DESCRIPTION (Adapted from the Applicant's Abstract): The primary aim of the proposed research is to evaluate the efficacy of Interpersonal Psychotherapy (IPT) as a treatment for antenatal depression. The treatment outcomes to be investigated in this study include the effects of IPT on the reduction of women's depressive symptoms and on their rates of remission from depression. Changes in social and marital adjustment which result from treatment will also be evaluated. The second aim of the proposed research is to identify factors that are associated with response to IPT, so that women who may benefit from IPT can be more accurately identified in the future. The third aim of the proposed research is to evaluate the effect of treatment with IPT during pregnancy on women's depressive symptoms during the puerperium. The fourth aim of the proposed research is to identify factors that are associated with high levels of postpartum depressive symptomatology among women receiving either IPT or the control treatment during pregnancy. A total of 110 women in their first and second trimesters of pregnancy will be recruited from Maternal Health Centers (MHC's) across the state of Iowa. This recruitment strategy will include women from a wide range of socioeconomic classes and both rural and urban settings. Women will be randomly assigned to treatment with IPT or to a treatment as usual condition. Women in the treatment as usual condition will receive treatment from physicians at their local MHC. The treatment as usual condition is designed to reflect the treatment that women currently receive for antenatal depression in the community, and to provide a valid test of the effectiveness of IPT. IPT will be delivered over 12 weeks during the antenatal period to women in the group receiving IPT. Assessments of women before, during, and after the completion of treatment will be conducted to evaluate its effectiveness. Women will also be followed for a year following delivery to assess their postpartum emotional and social adjustment. We expect that women treated with IPT will have significantly lower levels of depression and higher levels of social functioning than women in the control condition. We also expect that women receiving IPT will have significantly lower levels of depressive symptomatology during the puerperium than women in the control condition. We hypothesize that IPT will be an effective low-risk alternative to the use of medication during pregnancy.