Establishing the role of cochlear type II spiral ganglion sensory neurons in hearing: In one ear and out the other

确定耳蜗 II 型螺旋神经节感觉神经元在听力中的作用：一只耳朵内和另一只耳朵外

• 批准号: nhmrc : 1052463
• 负责人: Prof Allen Ryan
• 金额: $ 31.65万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/establishing-role-cochlear-hearing-ear/112275
• 关键词: Establishing; role; cochlear; type; II

Sound in one ear affects hearing in the other ear. This contralateral suppression is important for hearing attention and protection from noise damage. We will test the hypothesis that cochlear type II sensory neurons provide the sensory input for this process using models where neuronal development is altered, or the neurons are removed. The study addresses hearing disability in society, facilitating cochlear prosthesis development and the understanding of hearing loss.

一只耳朵的声音会影响另一只耳朵的听力。这种对侧抑制对于听力注意力和防止噪音损害非常重要。我们将使用改变神经元发育或去除神经元的模型来测试耳蜗 II 型感觉神经元为该过程提供感觉输入的假设。该研究针对社会中的听力障碍问题，促进人工耳蜗的开发和对听力损失的理解。