New Jersey Pediatric AIDS Clinical Trials Consortium

新泽西州儿科艾滋病临床试验联盟

• 批准号: 6732676
• 负责人: Paul E. Palumbo
• 金额: $ 122.34万
• 依托单位: UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-09-30 至 2007-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6732676
• 关键词: AIDS education /prevention; AIDS therapy; AIDS vaccines; HIV infections; antiAIDS agent; behavioral /social science research tag; children; clinical trial phase I; cooperative study; human immunodeficiency virus 1; human pregnant subject; human subject; human therapy evaluation; immunotherapy; opportunistic infections; outcomes research; pathologic process; patient oriented research; pediatric AIDS; vertical transmission

DESCRIPTION (provided by applicant): In response to RFA AI-00-015, the New Jersey Pediatric AIDS Consortium (NJ-PAC) is submitting this application to continue participation as a Pediatric AIDS Clinical Trials Unit (PACTU) affiliated with the Coordinating and Operations Center (CORC), led by Dr. Stephen Spector, to advance the research agenda of the PACTG. NJ-PAC investigators and resources offer a combination of experienced leadership, scientific contributions, and an extensive patient base in the context of a strong clinical infrastructure. Through this collaboration, NJ-PAC?s obstetrical, pediatric, and adolescent investigators will continue to enroll pregnant women, infants, children and adolescents into high priority Phase I, II and III clinical trials, with co-enrollment of these patients into long term outcome studies. This application details comprehensive plans that address all aspects of the future PACTG research agenda: Perinatal, Primary Therapy, Adolescence, Complications of HIV, and Immunology/Immune-Based Therapy. In addition, NJ-PAC and its investigators are active collaborators with national and international groups. The experience and contributions of our NJ-PAC investigators during the last four-year funding cycle and the large, diverse HIV-infected populations within the NJ-PAC service area, position NJ-PAC as a critical unit for the future success of the PACTG research agenda.

描述（由申请人提供）：为响应RFA AI-00-015，新 泽西岛儿童艾滋病联盟（NJ-PAC）将此申请提交给 继续参与儿科艾滋病临床试验单位（PACTU） 隶属于协调和运营中心（CORC），由博士领导。 斯蒂芬·斯佩克特，推进PACTG的研究议程。NJ-PAC 调查人员和资源提供了经验丰富的领导， 科学贡献，以及广泛的患者基础， 强大的临床基础设施。通过这次合作，NJ-PAC？S 产科、儿科和青少年研究者将继续招募 孕妇、婴儿、儿童和青少年纳入高度优先的第一阶段， II期和III期临床试验，这些患者共同入组长期 长期结果研究。该应用程序详细说明了全面的计划， 解决未来PACTG研究议程的各个方面：围产期，初级 治疗，青春期，艾滋病毒的并发症，免疫学/免疫基础 疗法此外，NJ-PAC及其调查人员是积极的合作者， 与国内和国际团体。的经验和贡献 我们的NJ-PAC调查人员在过去四年的资助周期和 NJ-PAC服务区内大量不同的艾滋病毒感染人群， 将新泽西-太平洋空军基地定位为太平洋空军基地未来成功的关键单位 研究议程。