Dartmouth Regional Pediatric Clinical Trials Unit

达特茅斯地区儿科临床试验单位

• 批准号: 9461963
• 负责人: Paul E. Palumbo
• 金额: $ 58.15万
• 依托单位: DARTMOUTH COLLEGE
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-23 至 2018-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9461963
• 关键词: Dartmouth; Regional; Pediatric; Clinical; Trials

Abstract Dartmouth is home to a robust pediatric academic program centered in the Children's Hospital at Dartmouth (CHaD). While it can demonstrate pockets of excellence in clinical trials targeting children and pregnant women, it lacks a coordinated home to resource such trial activities and to foster professional development. The IDeA States Pediatric Clinical Trials Network (ISPCTN) offers a timely opportunity to craft a center for pediatric clinical trials, to leverage existing resources and develop new ones, to recruit investigators and groups to this core, and to engage local as well as multi-center clinical trials. Organization of our regional presence in the form of the Dartmouth Regional Pediatric Clinical Trials Unit (DRP-CTU) will allow recruitment of a diverse pediatric population, including those who are rural and underserved. To accomplish this, we propose a partnership of three Enrollment Centers, one located at Dartmouth- Hitchcock-Lebanon (Coordinating Center), one at DH-Manchester (urban with large rural catchment area), and one at the Dartmouth CO-OP (extensive rural access) – to provide flexible and robust access to regional populations. A Senior Advisory Committee composed of campus leaders will provide guidance and support navigation of institutional challenges. We will also engage local and ISPCTN resources to establish a program of faculty and staff professional development and create a Mentoring Committee for pro-active implementation. Finally, we plan to stimulate and support our pediatric research community in the multicenter study of pediatric conditions and processes. We also plan to collaborate with our neighboring ISPCTN applicant - the University of Vermont Children's Hospital - and conduct a joint Pediatric Clinical Trials Forum annually. This initiative will provide a much-needed central coordinating platform for the conduct of pediatric clinical trials in the Dartmouth community. It will support existing and new investigators, expanding our clinical trials universe, stimulating expansion of our portfolio, and offering new opportunities for professional development with the resultant recruitment/training of new faculty and research staff. !

摘要 达特茅斯是一个强大的儿科学术项目的所在地，该项目以儿童医院为中心， 达特茅斯。虽然它可以在针对儿童的临床试验中表现出卓越的表现 和孕妇，它缺乏一个协调的家庭资源，这种试验活动，并促进 专业发展。IDEA国家儿科临床试验网络（ISPCTN）提供了及时的 有机会建立一个儿科临床试验中心，利用现有资源，开发新的 其中，招募调查人员和小组，以这一核心，并从事当地以及多中心 临床试验以达特茅斯地区儿科的形式组织我们的地区存在 临床试验单位（DRP-CTU）将允许招募不同的儿科人群，包括 他们生活在农村，得不到充分的服务。 为了实现这一目标，我们提出了三个招生中心的合作伙伴关系，一个位于达特茅斯- 希区柯克-黎巴嫩（协调中心），一个在DH-Manchester（城市与大农村集水区） 一个在达特茅斯CO-OP（广泛的农村接入）-提供灵活和强大的 进入区域人口。由校园领导组成的高级咨询委员会将 提供指导并支持机构挑战的导航。 我们还将利用当地和ISPCTN资源建立一个教职员工计划 专业发展，并建立一个指导委员会，积极实施。最后， 我们计划刺激和支持我们的儿科研究社区进行多中心研究， 儿科条件和过程。我们还计划与邻近的ISPCTN合作 申请人-佛蒙特大学儿童医院-并进行联合儿科临床试验 论坛每年。 这一举措将提供一个急需的中央协调平台， 达特茅斯社区的临床试验。它将支持现有和新的调查人员，扩大 我们的临床试验领域，刺激我们的产品组合的扩展，并为以下方面提供新的机会： 专业发展与新的教师和研究人员的招聘/培训。 !