MALDI TOF Mass Spectrometer

描述（由申请人提供）：加州大学伯克利分校化学学院正在寻求资金购买一台MALDI-TOF质谱仪。该仪器将被安置在质谱设施，并将提供给学生和工作人员在24小时，每周7天的基础上。为了满足NIH资助的研究人员对生物分子和聚合物分析日益增长的需求，该设施迫切需要新的最先进的仪器。虽然该设施在过去很幸运地获得了良好的仪器，但目前的许多质谱仪都变得相当陈旧，不能满足对高分子量树状大分子、寡核苷酸、蛋白质和碳水化合物的需求。下面列出了六个学院的研究，每个学院都将从内部开放获取的MALDI-TOF中受益匪浅。这些研究人员中有五位已经获得了NIH的资助，其中一位是该系最新的助理教授。仅这六个小组就包括81名博士后、研究生和本科生，他们将直接受益于该设备。

DESCRIPTION (provided by applicant): The College of Chemistry, at the University of California-Berkeley, is seeking funds for the purchase of a MALDI-TOF mass spectrometer. This instrument will be housed in the Mass Spectrometry facility and will be available to students and staff on a 24 hour, 7 days per week basis. The facility is in critical need of new state-of-the-art instrumentation in order to meet the growing demand for biomolecule and polymer analysis of its NIH funded researchers. Although the facility has been fortunate to secure good instrumentation in the past, many of the current mass spectrometers are becoming quite old and do not meet the needs for high molecular weight dendrimers, oligonucleotides, proteins and carbohydrates. The research of six faculties are listed below, each of who would benefit greatly from an in house, open access MALDI-TOF. Five of these researchers have established NIH funding, while one is the newest assistant professor in the department. These six groups, alone, include 81 postdoctoral associates, graduate and undergraduate students who will benefit directly from this equipment.