MINORITY PREDOCTORAL FELLOWSHIP PROGRAM

描述（由申请人提供）：“未选择论文”。我的研究兴趣是了解滋养细胞侵袭的调节和功能以及母体在怀孕期间发生的适应。为了更好地了解滋养细胞与母体脉管系统、免疫系统细胞和催乳素家族成员之间的关系，将进行研究。通过破译滋养细胞入侵子宫是如何被调节的，以及导致滋养细胞消失的原因，我们可以发现更多关于怀孕期间母胎环境的信息。关注滋养细胞侵袭的意义在于更好地了解和潜在地预防妊娠相关疾病，如先兆子痫和宫内生长受限。两者都与滋养层浸润有关，并导致母亲和胎儿的病理。

DESCRIPTION (provided by applicant): "No thesis selected". My research interests are in understanding the regulation and function of trophoblast invasion as well as the maternal adaptations that occur during pregnancy. Studies will be done to better understand the relationship between trophoblast cells and the maternal vasculature, cells of the immune system, and prolactin family members. By deciphering how trophoblast invasion into the uterus is regulated, and what causes their disappearance, more can be discovered about the maternal-fetal environment during pregnancy. The significance of focusing on trophoblast invasion is to better understand and potentially prevent pregnancy-associated conditions such as pre-eclampsia and intrauterine growth restriction. Both are correlated with shallow trophoblast invasion and lead to pathologies in the mother and fetus.