MINORITY PREDOCTORAL FELLOWSHIP PROGRAM

描述(申请人提供)：“未选论文”。我的研究兴趣是了解滋养细胞入侵的调节和功能，以及怀孕期间发生的母体适应。将进行研究，以更好地了解滋养细胞与母体血管系统、免疫系统细胞和催乳素家族成员之间的关系。通过破译滋养层细胞如何入侵子宫，以及是什么导致滋养层细胞的消失，可以更多地了解怀孕期间的母婴环境。关注滋养细胞侵袭的意义是为了更好地了解和潜在地预防妊娠相关疾病，如先兆子痫和宫内生长受限。两者都与浅层滋养细胞侵袭有关，并导致母亲和胎儿的病理改变。

DESCRIPTION (provided by applicant): "No thesis selected". My research interests are in understanding the regulation and function of trophoblast invasion as well as the maternal adaptations that occur during pregnancy. Studies will be done to better understand the relationship between trophoblast cells and the maternal vasculature, cells of the immune system, and prolactin family members. By deciphering how trophoblast invasion into the uterus is regulated, and what causes their disappearance, more can be discovered about the maternal-fetal environment during pregnancy. The significance of focusing on trophoblast invasion is to better understand and potentially prevent pregnancy-associated conditions such as pre-eclampsia and intrauterine growth restriction. Both are correlated with shallow trophoblast invasion and lead to pathologies in the mother and fetus.