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Genomics of Adaption to Climate Change in Rice

水稻适应气候变化的基因组学

基本信息

批准号：
2400447
负责人：
金额：
--
依托单位：
University of Southampton
依托单位国家：
英国
项目类别：
Studentship
财政年份：
2020
资助国家：
英国
起止时间：
2020 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=studentship-2400447
关键词：
Genomics Adaption Climate Change Rice

项目摘要

Feeding a growing population sustainably in the face of climate change requires us to resolve the genetic basis of crop tolerance to stress (especially temperature, precipitation and edaphic factors). Crops have reduced genetic diversity for stress tolerances compared to wild species; the analysis of crop-wild relatives can lead to the identification of adaptive genetic variation that can be bred into commercial cultivars. In this project, the student will use genome-scale data for wild rice to identify genes involved in environmental adaptation, confirm the role of these genes, and determine if the distributions of adaptive alleles have changed over time. Rice is a staple for almost half of the world population, therefore plentiful genomic data and seed material exists. Yet the data has not been exhaustively analysed, and we have identified a novel cutting-edge way to identify adaptive genetic variation. The three key stages are: Genomes of locally adapted wild rice and locally important cultivars will be analysed to identify genes involved in adaptation to soil and climate. Candidate genes will be functionally tested using transgenics. Sequencing of adaptive alleles from 20-100-year-old herbarium samples will assess how allele frequencies change over time, with implications for climate change resilience.

面对气候变化，可持续地养活不断增长的人口需要我们解决作物对压力（特别是温度，降水和土壤因素）耐受性的遗传基础。与野生物种相比，农作物的胁迫耐受性遗传多样性降低;对农作物-野生近缘种的分析可以鉴定出适应性遗传变异，这些变异可以培育成商业品种。在这个项目中，学生将使用野生稻的基因组规模数据来识别参与环境适应的基因，确认这些基因的作用，并确定适应性等位基因的分布是否随时间而变化。水稻是世界近一半人口的主食，因此存在丰富的基因组数据和种子材料。然而，这些数据还没有被彻底分析，我们已经确定了一种新的尖端方法来识别适应性遗传变异。三个关键阶段是：将分析适应当地的野生稻和当地重要品种的基因组，以确定与适应土壤和气候有关的基因。候选基因将使用转基因进行功能测试。对20-100年历史的植物标本馆样本中的适应性等位基因进行测序，将评估等位基因频率如何随时间变化，以及对气候变化适应能力的影响。