Evolutionary Genetics and Ecology of Trichromatic Vision

三色视觉的进化遗传学和生态学

• 批准号: 6700772
• 负责人: NATHANIEL Jay DOMINY
• 金额: $ 3.68万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-01-01 至 2004-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6700772
• 关键词: Cercopithecidae; Primates; animal genetic material tag; biochemical evolution; color visions; diet; ecology; environmental adaptation; field study; gene expression; genetic polymorphism; leaf; molecular genetics; nucleic acid sequence; nutrition related tag; polymerase chain reaction; statistics /biometry

DESCRIPTION (provided by applicant): Humans show considerable variation in trichromatic color vision, which is the presence of three retinal cones tuned to different wavelengths. Approximately 8 percent of Caucasian males, for example, show color vision abnormalities. This variation stands in contrast to the remarkable uniformity of vision found in Old World monkeys, apes, and the Neotropical genus of howling monkeys. Variations in these populations are extremely rare and, at the moment, it is unclear why trichromacy twice evolved so similarly in primates but in no other known mammal. The hypothesis that young, colored leaves may have selected for trichromatic color vision in primates has recently received support. Among mammals, however, molecular evidence on the color vision of specialized, non-primate frugivores and folivores is nonexistent. If indeed trichromacy is found in another mammal, it will refute the dogma that trichromacy is absent in non-primate mammals and, moreover, plausibly support one of the competing hypotheses for why it evolved. The Kloss gibbon, isolated for 500,000 years on the Mentawai Islands of Indonesia, is the most frugivorous ape ever observed. It may therefore model the conditions faced by our human ancestors and, like humans, may exhibit a high frequency of dichromacy. Molecular evidence on the color vision of the Kloss gibbon and a broad array of mammals with specialized diets will be obtained from DNA collected from a variety of sources, including feces and museum specimens. For the middle/long wavelength opsin(s), PCR-based gene isolation strategies will be implemented. All exons from the 2-or3 possible opsins will be entirely sequenced. For some of the non-primate species, it will be necessary to develop complete or partial genomic libraries. This study thus aims to explore the issues, implications, and evolutionary significance of color vision variation.

描述（由申请人提供）：人类在以下方面表现出相当大的差异 三色视觉，即三个视网膜锥体调节的存在 到不同的波长。大约 8% 的白人男性 例如，表现出色觉异常。这种变化与 在旧大陆的猴子、猿类和猿类中发现了惊人的视觉一致性 新热带地区的嚎叫猴属。这些人群的差异是 极其罕见，目前还不清楚为什么三色视觉会两次进化 在灵长类动物中也有类似的情况，但在其他已知的哺乳动物中却没有。假设 年轻的彩色叶子可能选择了三色视觉 灵长类动物最近得到了支持。然而，在哺乳动物中，分子 关于专门的非灵长类食果动物的色觉的证据 食叶动物是不存在的。如果在另一种哺乳动物中确实发现了三色视觉，那么 将驳斥非灵长类哺乳动物不存在三色视觉的教条， 此外，合理地支持了其进化原因的竞争假设之一。 克洛斯长臂猿，在明打威群岛与世隔绝 50 万年 印度尼西亚，是迄今为止观察到的最食果的猿类。因此它可以建模 我们人类祖先所面临的条件，并且像人类一样，可能会表现出 二色性频率高。关于色觉的分子证据 克洛斯长臂猿和一系列具有特殊饮食的哺乳动物将 从各种来源收集的 DNA 中获得，包括粪便和 博物馆标本。对于中/长波长视蛋白，基于 PCR 的基因 将实施隔离策略。 2-或3个可能的所有外显子 视蛋白将被完全测序。对于一些非灵长类动物来说， 有必要开发完整或部分基因组文库。因此本研究 旨在探讨问题、影响和进化意义 色觉变化。

项目成果

Expression and Evolution of Short Wavelength Sensitive Opsins in Colugos: A Nocturnal Lineage That Informs Debate on Primate Origins.

• DOI: 10.1007/s11692-013-9230-y
• 发表时间: 2013
• 期刊: EVOLUTIONARY BIOLOGY
• 影响因子: 2.5
• 作者: Moritz, Gillian L.;Lim, Norman T. -L.;Neitz, Maureen;Peichl, Leo;Dominy, Nathaniel J.
• 通讯作者: Dominy, Nathaniel J.

Polymorphism of visual pigment genes in the muriqui (Primates, Atelidae).

鼠类（灵长类动物，Atelidae）视觉色素基因的多态性。

• DOI: 10.1111/j.1365-294x.2005.02822.x
• 发表时间: 2006
• 期刊: Molecular ecology
• 影响因子: 4.9
• 作者: Talebi,MG;Pope,TR;Vogel,ER;Neitz,M;Dominy,NJ
• 通讯作者: Dominy,NJ

Ecological consequences of scaling of chew cycle duration and daily feeding time in primates.

灵长类动物咀嚼周期持续时间和每日进食时间缩放的生态后果。

• DOI: 10.1016/j.jhevol.2009.02.007
• 发表时间: 2009
• 期刊: Journal of human evolution
• 影响因子: 3.2
• 作者: Ross,CallumF;Washington,RhyanL;Eckhardt,Alison;Reed,DavidA;Vogel,ErinR;Dominy,NathanielJ;Machanda,ZarinP
• 通讯作者: Machanda,ZarinP