Does puff topography measurement alter smoking behavior?

烟气形貌测量会改变吸烟行为吗？

• 批准号: 6834675
• 负责人: MELISSA D BLANK
• 金额: $ 4.91万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-13 至 2007-09-12
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6834675
• 关键词: behavioral /social science research tag; biomedical equipment development; clinical biomedical equipment; clinical research; drug administration rate /duration; gas analyzer; human subject; inhalation drug abuse; nicotine; portable biomedical equipment; predoctoral investigator; psychopharmacology; smoking; smoking cessation; substance abuse related behavior; video recording system

DESCRIPTION (provided by applicant): Puff topography measurement plays an important role in elucidating the factors that maintain regular tobacco use. Generally, topography is assessed in laboratory settings via mouthpiece-based, desktop devices. Recently, a portable mouthpiece-based device became available for use in naturalistic settings. However, smoking behavior in any setting may be influenced by measurement equipment (i.e., the mouthpiece). Understanding the extent to which mouthpiece-based measurement equipment alters behavior is critical, and will require comparison of laboratory-based and portable devices with nonmouthpiece-based measurement. This proposal describes two studies. The first compares mouthpiece-based desktop and portable topography measurement with video recordings of participants' smoking in a laboratory. The second compares the more naturalistic mouthpiece-based device from study 1 with video recordings in a non-laboratory environment. Both studies use 30 smokers and within-subject designs to investigate whether a mouthpiece influences a variety of puff topography variables, including puff number, duration, and interpuff interval. Results from this project will help maximize the validity of future studies that rely on puff topography assessment. Conducting this research will provide valuable experience related to the responsible conduct of research with human participants, as well as issues related to data collection, analysis, and reporting across diverse research sites. These experiences will help me achieve my goal to become an independent drug abuse researcher.

描述（由申请人提供）： 抽吸地形测量在阐明维持规律烟草使用的因素方面起着重要作用。通常，在实验室环境中通过基于口承的台式设备评估形貌。最近，一种基于便携式吹嘴的装置可用于自然环境。然而，任何环境中的吸烟行为都可能受到测量设备的影响（即，吹口）。了解基于接口的测量设备改变行为的程度至关重要，并且需要将基于实验室的和便携式设备与非基于接口的测量进行比较。 本提案介绍了两项研究。第一个比较基于口承的桌面和便携式地形测量与参与者在实验室吸烟的视频记录。第二项研究比较了研究1中更自然的基于吹口的设备与非实验室环境中的视频记录。这两项研究均使用了30名吸烟者和受试者内设计，以调查吸嘴是否影响各种抽吸形貌变量，包括抽吸次数、持续时间和抽吸间隔。该项目的结果将有助于最大限度地提高未来研究的有效性，这些研究依赖于喷烟地形评估。进行这项研究将提供与人类参与者负责任地进行研究相关的宝贵经验，以及与不同研究地点的数据收集，分析和报告相关的问题。这些经历将帮助我实现成为一名独立的药物滥用研究人员的目标。