Does puff topography measurement alter smoking behavior?

描述（由申请人提供）： 烟气形貌测量在阐明维持正常烟草使用的因素方面发挥着重要作用。一般来说，地形是在实验室环境中通过基于咬嘴的桌面设备进行评估的。最近，一种基于便携式吹嘴的设备可在自然环境中使用。然而，任何环境下的吸烟行为都可能受到测量设备（即烟嘴）的影响。了解基于咬嘴的测量设备改变行为的程度至关重要，并且需要将基于实验室和便携式设备与非基于咬嘴的测量进行比较。 该提案描述了两项研究。第一个将基于吸嘴的桌面和便携式地形测量与参与者在实验室吸烟的视频记录进行比较。第二个将研究 1 中更自然的基于吹嘴的设备与非实验室环境中的视频录制进行比较。这两项研究均使用 30 名吸烟者和受试者内部设计来调查烟嘴是否影响各种抽吸形态变量，包括抽吸次数、持续时间和抽吸间隔。该项目的结果将有助于最大限度地提高依赖于烟团地形评估的未来研究的有效性。进行这项研究将提供与人类参与者负责任地进行研究相关的宝贵经验，以及与跨不同研究站点的数据收集、分析和报告相关的问题。这些经历将帮助我实现成为一名独立药物滥用研究者的目标。

DESCRIPTION (provided by applicant): Puff topography measurement plays an important role in elucidating the factors that maintain regular tobacco use. Generally, topography is assessed in laboratory settings via mouthpiece-based, desktop devices. Recently, a portable mouthpiece-based device became available for use in naturalistic settings. However, smoking behavior in any setting may be influenced by measurement equipment (i.e., the mouthpiece). Understanding the extent to which mouthpiece-based measurement equipment alters behavior is critical, and will require comparison of laboratory-based and portable devices with nonmouthpiece-based measurement. This proposal describes two studies. The first compares mouthpiece-based desktop and portable topography measurement with video recordings of participants' smoking in a laboratory. The second compares the more naturalistic mouthpiece-based device from study 1 with video recordings in a non-laboratory environment. Both studies use 30 smokers and within-subject designs to investigate whether a mouthpiece influences a variety of puff topography variables, including puff number, duration, and interpuff interval. Results from this project will help maximize the validity of future studies that rely on puff topography assessment. Conducting this research will provide valuable experience related to the responsible conduct of research with human participants, as well as issues related to data collection, analysis, and reporting across diverse research sites. These experiences will help me achieve my goal to become an independent drug abuse researcher.