NEI Institute Clinical Scientist Development Program

NEI 研究所临床科学家发展计划

• 批准号: 6895056
• 负责人: GORDON KENNETH KLINTWORTH
• 金额: $ 33.07万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-30 至 2009-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6895056
• 关键词: clinical research; health science research potential; medicine; training; vision

DESCRIPTION (provided by applicant): This is an institutional training grant proposal to educate the next generation of clinician-scientists for academic positions in Ophthalmology. For over 38 years, the Duke University Eye Center (DUEC) has been a national leader in training academic Ophthalmologists. The earliest generations of these trainees now serve in numerous leadership positions in academic medical centers across the country and abroad. They have roles as Deans, Department Chairs, and faculty members and serve as mentors for academicians. We propose to continue this tradition through an intensive program designed to provide the guidance, resources, and didactic teaching necessary to produce clinician-scientists for academic positions in Ophthalmology. We plan to select two trainees each year after their completion of a residency in Ophthalmology or Pathology for an intense 3 year educational program that will lead to independent peer-reviewed grant funding and a faculty position in an academic institution. The trainees will undergo an intensive didactic curriculum combined with a close mentorship by senior faculty at Duke University. Each trainee will receive mandatory training in areas of clinical research, genetics, statistics, scientific writing, grant preparation, ethics, and the responsible conduct of research. Each trainee will participate in significant original research and learn the essential skills to develop a successful and independent academic career. Additional aspects of the curriculum of each trainee will be tailored by the program director and lead mentor based upon the selected primary research track and his/her skills, background and career goals. We propose five primary research tracks: 1) Ophthalmic Genomics and Proteomics, 2) Ophthalmic Pathology, 3) Translational Medicine and Clinical Trials, 4) Clinic to Bench, 5) Outcomes and Health Policy. Because of an international shortage of Ophthalmic Pathologists involved in research, we will attempt to recruit Pathologists and train them for a research career to further knowledge about ocular diseases using tissue derived from patients and experimental models.

描述（由申请人提供）：这是一项机构培训资助提案，旨在为眼科学术职位培养下一代临床科学家。在过去的38年里，杜克大学眼科中心（DUEC）一直是培养学术眼科医生的国家领导者。这些最早的几代学员现在在全国和国外的学术医疗中心担任许多领导职务。他们担任院长、系主任和教员，并担任院士的导师。我们建议通过一个密集的项目来延续这一传统，该项目旨在提供必要的指导、资源和教学，以培养眼科学术职位的临床科学家。我们计划每年选择两名完成眼科或病理学住院医师培训的学员参加为期三年的高强度教育项目，这些项目将获得独立的同行评审资助，并在学术机构担任教职。受训者将在杜克大学高级教师的密切指导下接受密集的教学课程。每位受训者将接受临床研究、遗传学、统计学、科学写作、拨款准备、伦理和负责任的研究行为等领域的强制性培训。每个学员都将参与重要的原创研究，并学习发展成功和独立学术生涯的基本技能。每个学员课程的其他方面将由项目主管和首席导师根据所选的主要研究方向和他/她的技能、背景和职业目标量身定制。我们提出五个主要研究方向：1)眼科基因组学和蛋白质组学，2)眼科病理学，3)转化医学和临床试验，4)临床到实验室，5)结果和卫生政策。由于参与研究的眼科病理学家在国际上的短缺，我们将尝试招募病理学家并培训他们从事研究工作，以利用来自患者和实验模型的组织来进一步了解眼部疾病。