NEI Institute Clinical Scientist Development Program

NEI 研究所临床科学家发展计划

• 批准号: 7289697
• 负责人: GORDON KENNETH KLINTWORTH
• 金额: $ 95.81万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-30 至 2009-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7289697
• 关键词: Academic Medical Centers; Academic Training; Applications Grants; Area; Clinic; Clinical; Clinical Research; Clinical Trials; Country; Disease; Educational Curriculum; Educational process of instructing; Ethics; Experimental Models; Faculty; Funding; Generations; Genetic; Genomics; Goals; Grant; Health Policy; Institutes; Institution; International; Knowledge; Lead; Leadership; Learning; Mentors; Mentorship; Ophthalmologist; Ophthalmology; Outcome; Pathologist; Pathology; Patients; Peer Review Grants; Positioning Attribute; Preparation; Program Development; Proteomics; Recruitment Activity; Research; Residencies; Resources; Role; Scientist; Tissues; Training; Universities; Writing; base; career; design; eye center; member; next generation; programs; skills; statistics; translational medicine

DESCRIPTION (provided by applicant): This is an institutional training grant proposal to educate the next generation of clinician-scientists for academic positions in Ophthalmology. For over 38 years, the Duke University Eye Center (DUEC) has been a national leader in training academic Ophthalmologists. The earliest generations of these trainees now serve in numerous leadership positions in academic medical centers across the country and abroad. They have roles as Deans, Department Chairs, and faculty members and serve as mentors for academicians. We propose to continue this tradition through an intensive program designed to provide the guidance, resources, and didactic teaching necessary to produce clinician-scientists for academic positions in Ophthalmology. We plan to select two trainees each year after their completion of a residency in Ophthalmology or Pathology for an intense 3 year educational program that will lead to independent peer-reviewed grant funding and a faculty position in an academic institution. The trainees will undergo an intensive didactic curriculum combined with a close mentorship by senior faculty at Duke University. Each trainee will receive mandatory training in areas of clinical research, genetics, statistics, scientific writing, grant preparation, ethics, and the responsible conduct of research. Each trainee will participate in significant original research and learn the essential skills to develop a successful and independent academic career. Additional aspects of the curriculum of each trainee will be tailored by the program director and lead mentor based upon the selected primary research track and his/her skills, background and career goals. We propose five primary research tracks: 1) Ophthalmic Genomics and Proteomics, 2) Ophthalmic Pathology, 3) Translational Medicine and Clinical Trials, 4) Clinic to Bench, 5) Outcomes and Health Policy. Because of an international shortage of Ophthalmic Pathologists involved in research, we will attempt to recruit Pathologists and train them for a research career to further knowledge about ocular diseases using tissue derived from patients and experimental models.

描述（由申请人提供）：这是一个机构培训补助金的建议，以教育下一代的临床医生，科学家在眼科学术职位。38年来，杜克大学眼科中心（DUEC）一直是培养学术眼科医生的国家领导者。这些受训人员的最早一代现在在全国和国外的学术医疗中心担任许多领导职务。他们有作为院长，系主任和教师的角色，并作为导师的院士。我们建议通过一个旨在提供必要的指导，资源和教学，以生产临床科学家在眼科学术职位的强化计划继续这一传统。我们计划每年在完成眼科或病理学实习后选择两名学员进行为期3年的密集教育计划，这将导致独立的同行评审拨款资金和学术机构的教师职位。学员将接受密集的教学课程，并由杜克大学的高级教师进行密切的指导。每个学员将接受强制性培训，在临床研究，遗传学，统计学，科学写作，拨款准备，道德和负责任的研究行为领域。每个学员将参加重要的原创研究，并学习基本技能，以发展成功和独立的学术生涯。每个受训者课程的其他方面将由项目主任和首席导师根据选定的主要研究方向及其技能、背景和职业目标进行量身定制。我们提出了五个主要研究方向：1）眼科基因组学和蛋白质组学，2）眼科病理学，3）转化医学和临床试验，4）临床到实验室，5）结果和健康政策。由于国际上缺乏参与研究的眼科病理学家，我们将尝试招募病理学家并培训他们从事研究工作，以进一步了解来自患者和实验模型的组织的眼科疾病。