NEI Mentored Clincial Scientist Development Program Award (K12)

NEI 指导临床科学家发展计划奖 (K12)

• 批准号: 8293265
• 负责人: GORDON KENNETH KLINTWORTH
• 金额: $ 24.18万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-30 至 2015-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8293265
• 关键词: Academic Medical Centers; Academic Training; Applications Grants; Area; Clinic; Clinical Oncology Supplement (K12); Clinical Research; Clinical Trials; Country; Educational Curriculum; Educational process of instructing; Ethics; Experimental Models; Faculty; Funding; Generations; Genetic; Genomics; Goals; Grant; Health Policy; Individual; Institution; International; Lead; Leadership; Learning; Mentors; Mentorship; Ophthalmologist; Ophthalmology; Outcome; Pathologist; Pathology; Patients; Peer Review Grants; Positioning Attribute; Preparation; Program Development; Proteomics; Recruitment Activity; Research; Residencies; Resources; Role; Scientist; Tissues; Training; Universities; Writing; base; bench to bedside; career; design; didactic education; eye center; member; next generation; programs; responsible research conduct; skills; statistics; translational medicine

This is an institutional training grant proposal to educate the next generation of clinician-scientists for academic positions in Ophthalmology. For over 38 years, the Duke University Eye Center (DUEC) has been a national leader in training academic Ophthalmologists. The earliest generations of these trainees now serve in numerous leadership positions in academic medical centers across the country and abroad. They have roles as Deans, Department Chairs, and faculty members and serve as mentors for academicians. We propose to continue this tradition through an intensive program designed to provide the guidance, resources, and didactic teaching necessary to produce clinician-scientists for academic positions in Ophthalmology. We plan to select two trainees each year after their completion of a residency in Ophthalmology or Pathology for an intense 3 year educational program that will lead to independent peer-reviewed grant funding and a faculty position in an academic institution. The trainees will undergo an intensive didactic curriculum combined with a close mentorship by senior faculty at Duke University. Each trainee will receive mandatory training in areas of clinical research, genetics, statistics, scientific writing, grant preparation, ethics, and the responsible conduct of research. Each trainee will participate in significant original research and learn the essential skills to develop a successful and independent academic career. Additional aspects of the curriculum of each trainee will be tailored by the program director and lead mentor based upon the selected primary research track and his/her skills, background and career goals. We propose five primary research tracks: (1) translational medicine and clinical trials, (2) clinics and bedside to the bench, (3) Ophthalmic genomics and proteomics, (4) ophthalmic pathology, (5) outcomes and health policy. Because of an international shortage of Ophthalmic Pathologists we will attempt to recruit and appropriate individuals for a research career involving the use of ocular tissues derived from patients and experimental models.

这是一项机构培训拨款提案，旨在教育下一代临床医生科学家担任眼科学术职位。 38 年来，杜克大学眼科中心 (DUEC) 一直在培养学术眼科医生方面处于全国领先地位。这些学员的最早几代现在在国内外学术医疗中心担任众多领导职务。他们担任院长、系主任和教员，并担任院士的导师。我们建议通过一项强化计划来延续这一传统，该计划旨在提供必要的指导、资源和教学，以培养担任眼科学术职位的临床医生科学家。我们计划每年选择两名学员完成眼科或病理学住院医师培训后参加为期 3 年的强化教育计划，该计划将获得独立同行评审的资助资金和学术机构的教职职位。学员将接受密集的教学课程以及杜克大学高级教师的密切指导。每位学员都将接受临床研究、遗传学、统计学、科学写作、拨款准备、伦理学和负责任的研究行为等领域的强制性培训。每位学员都将参与重要的原创研究，并学习发展成功且独立的学术生涯的基本技能。项目总监和首席导师将根据所选的主要研究方向及其技能、背景和职业目标，为每位学员课程的其他方面进行定制。我们 提出五个主要研究方向：（1）转化医学和临床试验，（2）诊所和床边工作台，（3）眼科基因组学和蛋白质组学，（4）眼科病理学，（5）结果和健康政策。由于国际上眼科病理学家短缺，我们将尝试招募和合适的人员从事涉及使用来自患者和实验模型的眼组织的研究职业。