Evaluation of tissue engineered decellularised biphasic constructs for periodontal regeneration

组织工程脱细胞双相结构对牙周再生的评价

• 批准号: nhmrc : 1086181
• 负责人: Prof Mark Bartold
• 金额: $ 38.54万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/evaluation-tissue-engineered-periodontal-regeneration/519121
• 关键词: Evaluation; tissue; engineered; decellularised; biphasic

This project aims to regenerate the tissues lost as a result of gum disease. This will be done using scaffolds that replicate the complex structure of periodontal tissues.The scaffolds will be loaded with cells and allowed to mature before the cellular component is removed. The resultant construct is then inserted back into periodontal defects where it will be repopulated by host cells. This approach has the potential to be developed into an off-the-shelf clinical treatment.

该项目旨在再生因牙龈疾病而失去的组织。这将使用复制牙周组织复杂结构的支架来完成。支架将装载细胞，并在细胞成分被去除之前使其成熟。然后将所得的结构插入牙周缺损中，在那里它将被宿主细胞重新填充。这种方法有可能发展成为一种现成的临床治疗方法。