Periodontal mesenchymal stem cells for periodontal regeneration

牙周间充质干细胞用于牙周再生

• 批准号: nhmrc : 299009
• 负责人: Prof Mark Bartold
• 金额: $ 23.87万
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2004
• 资助国家: 澳大利亚
• 起止时间: 2004-01-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/periodontal-mesenchymal-stem-periodontal-regeneration/76307
• 关键词: Periodontal; mesenchymal; stem; cells; periodontal

Dental diseases affecting the gums (periodontal disease) are extremely prevalent in our society. The effects of periodontal disease can be particularly severe as loss of support for the teeth leads to loose teeth and severely compromised masticatory function. If left untreated, the associated pain and loss of function may necessitate extraction of the teeth. We have recently identified cells residing in the periodontal ligament which may be adult stem cells. This project will further characterize these cells and explore whether they can be used to restore periodontal tissues damaged by periodontal disease.

影响牙龈的牙科疾病（牙周病）在我们的社会中非常普遍。牙周病的影响可能特别严重，因为失去对牙齿的支持会导致牙齿松动和严重损害咀嚼功能。如果不治疗，相关的疼痛和功能丧失可能需要拔牙。我们最近已经确定了细胞驻留在牙周膜，这可能是成人干细胞。该项目将进一步表征这些细胞，并探索它们是否可用于修复牙周病损伤的牙周组织。