Multichannel Sensory Neurophysiology System

描述（由申请人提供）：本提案的目标是继续开发用于单单位神经生理学的多通道数据采集和刺激演示包。将创建新的界面和开发工具，以帮助调查人员利用第一阶段软件的灵活性。将继续开发用于多通道尖峰处理的实时数字信号处理（DSP）算法，利用TDT的System 3硬件的实时能力。最后，强大的新的后处理程序多通道尖峰排序和分析将被纳入。该系统的基本优点是其灵活性和可扩展性。可适应的平台允许呈现和采集几乎任何信号类型。多通道单个单元、局部场电位、EEG、EMG、发声、传感器数据等可以被采集并集成到单个数据结构中。通过单个集成软件包和一组同步硬件模块控制采集和刺激。实时实验控制和刺激传递在同一系统中的多通道数据采集和分析的集成允许基于神经或行为反应的动态实验控制和刺激修改。

DESCRIPTION (provided by applicant): The goal of this proposal is to continue the development of a multichannel data acquisition and stimulus presentation package for single-unit neurophysiology. New interfaces and development tools will be created to help investigators harness the flexibility of the Phase I software. Continuing development of real-time digital signal processing (DSP) algorithms for multichannel spike processing will be carried out, exploiting the real-time capabilities of TDT's System 3 hardware. Finally, powerful new post-processing routines for multichannel spike sorting and analysis will be incorporated. The fundamental advantage of this system is its flexibility and extensibility. The adaptable platform allows for virtually any signal type to be presented and acquired. Multichannel single unit, local field potentials, EEG, EMG, vocalizations, sensor data, etc. can be acquired and integrated into a single data structure. Acquisition and stimulation are controlled through a single integrated software package, and through a set of synchronized hardware modules. The integration of real-time experimental control and stimulus delivery in the same system as multi-channel data acquisition and analysis allows for dynamic experimental control and stimulus modification based on neural or behavioral responses.