Multichannel Sensory Neurophysiology System

描述（由申请人提供）：本提案的目标是继续开发用于单单元神经生理学的多通道数据采集和刺激呈现包。将创建新的接口和开发工具，以帮助研究人员利用第一阶段软件的灵活性。将继续开发用于多通道尖峰处理的实时数字信号处理（DSP）算法，利用TDT系统3硬件的实时能力。最后，强大的新后处理程序的多通道尖峰排序和分析将纳入。该系统的根本优点是其灵活性和可扩展性。适应性强的平台允许几乎任何信号类型的呈现和获取。多通道单单元、局部场电位、脑电图、肌电图、发声、传感器数据等可以被采集并集成到一个单一的数据结构中。采集和刺激通过一个单一的集成软件包，并通过一组同步的硬件模块进行控制。实时实验控制和刺激传递与多通道数据采集和分析在同一系统中的集成允许基于神经或行为反应的动态实验控制和刺激修改。

DESCRIPTION (provided by applicant): The goal of this proposal is to continue the development of a multichannel data acquisition and stimulus presentation package for single-unit neurophysiology. New interfaces and development tools will be created to help investigators harness the flexibility of the Phase I software. Continuing development of real-time digital signal processing (DSP) algorithms for multichannel spike processing will be carried out, exploiting the real-time capabilities of TDT's System 3 hardware. Finally, powerful new post-processing routines for multichannel spike sorting and analysis will be incorporated. The fundamental advantage of this system is its flexibility and extensibility. The adaptable platform allows for virtually any signal type to be presented and acquired. Multichannel single unit, local field potentials, EEG, EMG, vocalizations, sensor data, etc. can be acquired and integrated into a single data structure. Acquisition and stimulation are controlled through a single integrated software package, and through a set of synchronized hardware modules. The integration of real-time experimental control and stimulus delivery in the same system as multi-channel data acquisition and analysis allows for dynamic experimental control and stimulus modification based on neural or behavioral responses.