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EXAMINING THE RELATIONSHIP BETWEEN MATRIPTASE-2 AND HEMOJUVELIN, TWO ESSENTIAL REGULATORS OF IRON HOMEOSTASIS

EXAMINING THE RELATIONSHIP BETWEEN MATRIPTASE-2 AND HEMOJUVELIN, TWO ESSENTIAL REGULATORS OF IRON HOMEOSTASIS
检查铁稳态的两个重要调节剂 MATRIPTASE-2 和血幼素之间的关系
批准号：
nhmrc : 613643
负责人：
Dr Daniel Wallace
金额：
$35.58万
依托单位：
Queensland Institute of Medical Research
依托单位国家：
澳大利亚
项目类别：
NHMRC Project Grants
财政年份：
2010
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2010-01-01 至 2012-12-31
来源：
https://researchdata.edu.au/examining-relationship-matriptase-iron-homeostasis/96487
关键词：
EXAMININGRELATIONSHIPBETWEENMATRIPTASEHEMOJUVELIN

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中文摘要
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英文摘要
The control of iron levels is important in health and well being. Too little can lead to iron deficiency and anaemia, conversly too much can lead to haemochromatosis and tissue damage. We will examine the role of two proteins, matriptase-2 and hemojuvelin that when mutated cause iron deficiency or iron overload respectively. We will study how these proteins interact and work in opposite directions to control iron levels. The results will help to develop new therapeutics for iron disorders.
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  • 批准号：
    nhmrc : 1100088
  • 项目类别：
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  • 资助金额：
    $59.57万
  • 财政年份：
    2016
  • 负责人：
    Dr Daniel Wallace
  • 依托单位：
    Queensland University of Technology
SARA: Delineating its Association with the Onset and Development of Liver Fibrosis
  • 批准号：
    nhmrc : GNT1100088
  • 项目类别：
    Project Grants
  • 资助金额：
    $86.6万
  • 财政年份：
    2016
  • 负责人：
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  • 依托单位：
    Queensland University of Technology
Delineating the Relationship between Iron and Peroxisomal Disorders: The Role of the Peroxisomal Enzyme GNPAT in Iron-Overload Disorders
  • 批准号：
    nhmrc : GNT1082224
  • 项目类别：
    Project Grants
  • 资助金额：
    $67.45万
  • 财政年份：
    2015
  • 负责人：
    Dr Daniel Wallace
  • 依托单位：
    Queensland University of Technology
Delineating the Relationship between Iron and Peroxisomal Disorders: The Role of the Peroxisomal Enzyme GNPAT in Iron-Overload Disorders
  • 批准号：
    nhmrc : 1082224
  • 项目类别：
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  • 资助金额：
    $46.73万
  • 财政年份：
    2015
  • 负责人：
    Dr Daniel Wallace
  • 依托单位：
    Queensland University of Technology
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