Conference--Nucleic Acid Enzymes

会议--核酸酶

• 批准号: 6809005
• 负责人: Robert Landick
• 金额: $ 0.2万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-07-15 至 2005-07-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6809005
• 关键词: DNA directed RNA polymerase; RNA directed DNA polymerase; enzyme activity; enzymes; exodeoxyribonuclease; meeting /conference /symposium; nucleic acids; nucleoproteins; restriction endonucleases; travel

DESCRIPTION (provided by applicant): The meeting entitled "NUCLEIC ACID ENZYMES: STRUCTURES, MECHANISMS AND NOVEL APPLICATIONS" will focus on the structure, mechanisms, biological roles, and medical relevance of enzymes that act on DNA and RNA. The meeting will attract a broad cross-disciplinary group of scientists with expertise in structural biology, biochemistry, cell biology. This meeting will be the fifth sponsored by the Federation of American Societies of Experimental Biology (FASEB) in the areas of nucleic and enzymologist; the most recent was in 2002. The meeting provides a unique form for the explosion of information on enzymes that act on nucleic acids, the central role of DNA and RNA enzymologist in biotechnology, and the growing list of metabolic disorders and diseased in which nucleic acid enzymes are implicated. By bringing together structural biologists, biochemists, cell biologists and clinicians to discuss common interests, new insights and interdisciplinary collaboration will be fostered. The Scientific Program will consist of eight sessions of oral presentations by distinguished invited speakers in the following subject areas: (1) Transesterification enzymes; (2) Catalysis of phosphoryl transfer by proteins and RNA; (3) Transcription and RNA polymerases; (4) Histone modifications and chromatin remodeling; (5) Enzymology of DNA replication; 6) Single-molecule studies; (7) RNA processing; and (8) Recognition and processing of DNA damage. The organizers have recruited leading investigators to serve as discussion leaders for these sessions. The Program will also include daily poster sessions. All attendees will be encouraged to present posters on their research. To encourage career development of junior scientists, six outstanding posters from the ranks of graduate students and post-doc attendees will be selected for short oral presentations. The FASEB 2004 meeting aims to highlight several emerging themes in nucleic acids Enzymology; the rapidly expanding application of single-molecule methods to study of nucleic acid enzymes, the interplay between chromatin structure and DNA metabolism, the parallels between enzymes involved in DNA metabolism and those of the RNA world, and the burgeoning impact of nucleic acid enzymes on biotechnology and medicine. The intimate format of the conference is designed to promote free exchange of information and ideas among researchers who work on diverse aspects of the RNA and DNA enzymes - thereby expediting research in both fields.

描述(由申请者提供)：题为“核酸酶：结构、机制和新应用”的会议将集中讨论作用于DNA和RNA的酶的结构、机制、生物学作用和医学意义。这次会议将吸引具有结构生物学、生物化学和细胞生物学专业知识的跨学科科学家组成的广泛小组。这次会议将是美国实验生物学学会联合会(FASE B)在核和酶领域主办的第五次会议；最近一次是在2002年。会议提供了一种独特的形式，提供了关于作用于核酸的酶的信息爆炸，DNA和RNA酶学家在生物技术中的核心作用，以及与核酸酶有关的代谢紊乱和疾病的日益增多的清单。通过将结构生物学家、生物化学家、细胞生物学家和临床医生聚集在一起讨论共同的兴趣，将促进新的见解和跨学科合作。 科学计划将包括以下主题领域的杰出特邀演讲者的八次口头陈述：(1)酯交换酶；(2)蛋白质和RNA对磷酸转移的催化；(3)转录和RNA聚合酶；(4)组蛋白修饰和染色质重塑；(5)DNA复制的酶学；6)单分子研究；(7)RNA加工；以及(8)DNA损伤的识别和处理。组织者招募了主要的调查人员担任这些会议的讨论负责人。该计划还将包括每日张贴海报的环节。所有与会者将被鼓励展示关于他们的研究的海报。为了鼓励初级科学家的职业发展，将从研究生和博士后参与者队伍中挑选六名优秀海报进行简短的口头演示。 FASE B 2004会议旨在突出核酸酶学中的几个新兴主题；单分子方法在核酸酶研究中的迅速扩大的应用；染色质结构和DNA代谢之间的相互作用；参与DNA代谢的酶与RNA世界的酶之间的相似性；以及核酸酶对生物技术和医学的迅速影响。会议的亲密形式旨在促进从事RNA和DNA酶不同方面工作的研究人员之间的信息和思想的自由交流-从而加快这两个领域的研究。