GRC on Musculoskeletal Biology & Bioengineering

描述(由申请人提供)： 肌肉骨骼系统的研究涵盖了许多跨学科领域，主要是生物学和生物工程，并在临床领域有最终的应用，包括矫形外科、风湿病和放射学。戈登肌肉骨骼生物学和生物工程研究会议(前身为生物工程和整形外科科学)一直是展示和讨论该领域新信息和未发表信息的主要论坛，并一直导致新的见解、新的互动、新的合作和新的研究方向。 本申请寻求对2004年7月24-30日举行的第12届这样的戈登研究会议的部分支持。上一次会议于2002年7月28日至8月2日举行。有123名注册参与者参加了一场几乎满负荷的会议，与会者包括来自学术界、工业界和政府部门的不同职业发展阶段的人士。会议被与会嘉宾评为“杰出”。这次会议的形式传统上是每隔一年夏天在新汉普郡的一所小型私立学校举行，为工程师、生物学家和临床医生之间的集中互动提供了一个独特的环境。 即将到来的会议的计划建立在前一次会议的成功传统的基础上，采取了广泛的方法来了解肌肉骨骼组织的组成、结构、新陈代谢和生物力学功能。成立了一个科学咨询委员会，该委员会是一个持续的规划资源。计划召开的会议的主题是“骨科组织工程：从基础科学到临床应用”。它将研究与多种组织相关的主题，以及单个组织和结构，包括骨、软骨、椎间盘、韧带、半月板和肌腱。这些横跨多个组织的主题包括生物材料制造、细胞来源、组织/材料界面的整合、表面润滑、骨骼发育、生长和再生、全关节置换的见解、体内环境以及基础研究向临床实践的转化。将讨论的骨骼结构包括膝盖、臀部、肩部和脊柱。此外，杰出的演讲者还将提供“矫形外科成功治疗的工程珍珠”的讲座。计划举行的会议的形式基本上保持不变，有充足的时间进行正式和非正式讨论。从有前途的实习生到资深科学家的研究人员都将被鼓励参加。

DESCRIPTION (provided by applicant): The study of the musculoskeletal system encompasses a number of interdisciplinary fields, primarily biology and bioengineering, and has ultimate applications in clinical areas including orthopaedic surgery, rheumatology, and radiology. The Gordon Research Conference on Musculoskeletal Biology and Bioengineering (formerly called Bioengineering and Orthopaedic Sciences) has been the premiere forum for presentation and discussion of new and unpublished information in the field, and has consistently led to new insights, new interactions, new collaborations, and new research directions. This application seeks partial support for the 12th such Gordon Research Conference, July 24-30, 2004. The previous conference was held July 28-August 2, 2002. There were 123 registered participants for a near full capacity conference with the desired mix of individuals from academia, industry, and government, at various stages of career development. The conference was rated as "outstanding" by participants. The format of this conference, traditionally held in a small private school in New Hampshire every other summer, provides a unique environment for focused interaction between engineers, biologists, and clinicians. The planning of the upcoming conference has built upon the successful tradition of previous conference, taking a broad approach to understanding the composition, structure, metabolism, and biomechanical functions of musculoskeletal tissues. A Scientific Advisory Committee was formed and is a continuing resource for planning. The theme of the planned conference is "Orthopaedic Tissue Engineering: Basic Science to Clinical Application". It will examine topics relevant to multiple tissues, as well as individual tissues and structures, including bone, cartilage, intervertebral disc, ligament, meniscus, and tendon. The topics cross-cutting multiple tissues include biomaterial fabrication, cell sources, integration at tissue/material interfaces, lubrication at surfaces, skeletal development, growth and regeneration, insights from total joint replacement, the in vivo environment, and translation of basic research to clinical practice. Skeletal structures to be discussed include the knee, hip, shoulder, and spine. Also, distinguished speakers will provide lectures on "Pearls for Engineering Successful Treatments in Orthopaedic Surgery." The format of the planned conference remains essentially unchanged, with ample time for formal and informal discussions. Investigators ranging from promising trainees to senior scientists will be encouraged to attend.