7th ASM Conference on Candida and Candidiasis

描述(申请人提供)：白色念珠菌是一种寄生在皮肤和粘膜表面的共生菌。它也是这些表面的机会性疾病以及内部播散性疾病的病原体。虽然皮肤和粘膜表面的感染可能是导致严重发病率的一个原因，每年影响数百万美国人，但它们并不像播散性疾病那样危及生命。20世纪80年代中期，S被越来越多的研究者吸引到疾病发病机制的研究中。针对这一群体之间交流意见的需要，1987年举行了第一届关于念珠菌和念珠菌病的会议，约有115人参加了会议。从那时起，不仅研究人员的数量增加了，疾病患者的数量也增加了。不幸的是，口腔粘膜疾病是艾滋病的一种几乎普遍的并发症，念珠菌现在已成为医院内血流感染的第四大原因。近年来，出现了对唑类耐药菌株，非白念珠菌菌株的出现频率增加，特别是那些天生耐药的菌株。 该会议每三年举行一次，是研究念珠菌感染的生物学、流行病学和发病机制的研究人员的首要论坛。然而，在2002年第6次会议上，绝大多数人投票赞成将该次会议列入两年的时间表。因此，第七届会议将于2004年3月24日至28日在得克萨斯州奥斯汀的凯悦酒店举行。第7届会议的目标是继续提供论坛，介绍最先进的研究成果，并让研究人员非正式地会面和讨论他们的工作。本届大会预计将有300-400人出席，并发布150-200张海报。口头和/或海报会议将涵盖的主题包括：1)交配和遗传学，2)流行病学和种群研究，3)信号和形态发生，4)生物膜和病原体相互作用，5)基因组学和蛋白质组学，6)药物和耐药性，7)细胞壁和表面分子，8)诊断和治疗，9)宿主反应。演讲者和与会者预计将代表念珠菌研究人员的国际社会，既有现有的和新的研究人员，也有出席的学生和受训人员。除了至少12名研究生和博士后助理外，许多演讲者将从摘要中挑选出来。美国国立卫生研究院通过各种机构和项目，慷慨地支持了本次会议和前两届会议的许多美国演讲者和与会者，并希望国家卫生研究院与ASM和私人来源一起，为即将到来的2004年第7届大会提供财政援助。

DESCRIPTION (provided by applicant): Candida albicans is a commensal that colonizes skin and mucosal surfaces. It is also an agent of opportunistic disease of these surfaces as well as internal disseminated disease. While infections of cutaneous and mucosal surfaces may be a cause of significant morbidity and affect millions of Americans annually, they are not life threatening as is disseminated disease. In the mid-1980's a growing number of researchers were attracted to the study of pathogenesis of disease. In response to the need for exchange of ideas among this group, the first ASM Conference on Candida and Candidiasis was held in 1987 with an attendance of about 115. Since this time not only have the number of researchers grown but so have the number of patients with disease. Oral mucosal disease is unfortunately a nearly universal complication of AIDS and Candida has now become the fourth leading cause of nosocomial blood stream infections. In recent years there has been an emergence of azole resistant strains and increased frequency of non-albicans isolates, particularly those that are inherently drug resistant. This conference has been held every three years and is the premier forum for researchers engaged in study of the biology, epidemiology, and pathogenesis of candidal infection. However, at the 6th Conference in 2002 a large majority voted that the meeting by placed on a two-year schedule. Accordingly, the 7th Conference will be held March 24-28, 2004 at the Hyatt Regency in Austin, Texas. The goal of the 7th Conference is to continue to provide the forum to present the state of the art research and for investigators to meet and discuss their work informally. This 7th Conference is expected to have an attendance of 300 - 400 and the presentation of 150-200 posters. The topics that will be covered in the oral and/or poster sessions include: 1) mating and genetics, 2) epidemiology and population studies, 3) signaling and morphogenesis, 4) biofilms and pathogen interactions 5) genomics and proteomics, 6) drugs and resistance, 7) cell wall and surface molecules, 8) diagnosis and treatment, and 9) host response. Speakers and attendees are expected to represent the international community of Candida researchers with both established and new investigators as well as students and trainees present. Many of the speakers, in addition to at least 12 graduate students and postdoctoral associates, will be selected from abstracts. NIH through various institutes and programs has generously supported many of the American presenters and attendees of this conference, as well as the previous two conferences and it is hoped that NIH will join ASM and private sources in providing financial assistance for this upcoming 7th Conference in 2004.