9th International Workshop on Developmental Nephrology

描述（由申请人提供）： 本申请是对将于南澳巴罗萨谷（Barossa Valley）（2004年8月25日至27日）举行的第9届国际发育性肾脏学研讨会的部分支持请求。在过去的几十年里，发育肾生理学的学科沿着着儿科肾脏病学的诞生而发展。到1980年，全世界致力于这一领域的研究人员数量已经增加到在纽约举行的第一届国际肾脏发育生理学研讨会的程度。这一首次研讨会的成功导致了随后每隔3年组织一次研讨会，每次研讨会都与国际儿科肾病协会（IPNA）三年一次的大会相结合。该研讨会的目的是提供一个全面的分析国家的最先进的发育肾病学。尽管对发育中的肾脏的研究最初主要是儿科肾病学家的领域，但最近细胞和分子生物学以及肾脏疾病的分子遗传学的爆炸导致许多学科的研究人员将注意力集中在发育中的肾脏上。因此，讲习班将包括儿科肾病学、肾脏医学、生理学、细胞生物学、发育生物学、病理学、分子生物学和遗传学等学科的研究人员参加。第一天将讨论健康和疾病中肾脏和GU道模式的分子控制。第二天将集中在肾小球，肾小管和脉管系统水平的3D结构模式。正常上皮细胞分化的过程也将被讨论，包括极性的建立和个体发育的管状运输，以及信号通路的调节。最后一天将强调我们对终末分化缺陷和肾脏对损伤的反应的理解的新进展，重点是发育程序的重演。两个海报会议将提供一个机会，介绍免费通信。通过允许充足的时间进行提问和回答，该计划旨在作为一个论坛，有利于交流与发育中的肾脏的生物学，病理生理学和遗传学有关的新知识，技术和概念。会议将在巴罗萨谷度假村举行，这是进行这种互动的最佳地点，就在南澳阿德莱德举行的第13届IPNA大会（2004年8月29日至9月2日）之前举行。

DESCRIPTION (provided by applicant): This application is a request for partial support for the 9th International Workshop on Developmental Nephrology, to be held in the Barossa Valley, South Australia (August 25-27, 2004). The discipline of developmental renal physiology evolved along with the birth of pediatric nephrology over the past several decades. By 1980, the number of investigators in the world dedicated to this field had increased to the point where the 1st International Workshop on Developmental Renal Physiology was held in New York. The success of this initial Workshop led to the organization of subsequent Workshops at 3-year intervals, each in conjunction with the triennial Congress of the International Pediatric Nephrology Association (IPNA). The aim of the Workshop is to provide a comprehensive analysis of the state-of-the-art of developmental nephrology. Whereas investigation of the developing kidney had initially been chiefly the province of pediatric nephrologists, the recent explosion in cell and molecular biology as well as the molecular genetics of renal disease has resulted in the recruitment of investigators from many disciplines to focus their attention on the developing kidney. Thus, the Workshop will include the participation of investigators in disciplines including pediatric nephrology, renal medicine, physiology, cell biology, developmental biology, pathology, molecular biology and genetics. The first day will address the molecular control of patterning in the kidney and GU tract in health and disease. The second day will focus on patterning for 3D architecture at the level of the glomerulus, tubules and vasculature. Processes involved in normal epithelial differentiation will also be discussed, including establishment of polarity and ontogeny of tubular transport, and regulation by signaling pathways. The final day will highlight new advances in our understanding of defects in terminal differentiation and the response of the kidney to injury, with an emphasis on recapitulation of developmental programs. Two poster sessions will provide an opportunity for presentation of free communications. By allowing ample time for questions and answers, the program is designed to serve as a forum conducive to the exchange of new knowledge, techniques, and concepts relating to the biology, pathophysiology, and genetics of the developing kidney. The meeting will be held at Barossa Valley Resort, an optimal venue for such interaction, immediately preceding the 13th IPNA Congress in Adelaide, South Australia (August 29-September 2, 2004).