A Simple Point of Care White Blood Cell Count Test

简单的护理点白细胞计数测试

• 批准号: 6943868
• 负责人: Wai Tak Law
• 金额: $ 27.87万
• 依托单位: PORTASCIENCE, INC.
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-09-17 至 2006-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6943868
• 关键词: biomedical equipment development; blood cell count; cell sorting; clinical research; consumable /disposable biomedical equipment; health care personnel; home health care; human subject; leukocyte count; portable biomedical equipment; reflection spectrometry

DESCRIPTION (provided by applicant): Development of a finger-stick white blood cell (WBC) count assay method using a disposable test strip and a palm-size reader is proposed. The method will estimate the WBC count in minutes in a non-laboratory setting such as the patient's home. Preliminary data obtained with manually assembled prototypes have demonstrated the feasibility of the proposed method. A simple point-of-care (POC) method for measuring a WBC count will give healthcare providers a portable means of monitoring their cancer patients undergoing chemotherapy. Currently, there is no inexpensive and accurate method available. The proposed device will increase chemotherapy scheduling efficiency by allowing healthcare providers to obtain a WBC count before the patient comes in for therapy. This will in turn reduce health costs. POC applications for the proposed device have a potential worldwide market of $160 million annually. In Phase II, we propose to scale-up the device, develop a palm-size reader, thoroughly test the assay system, and prepare for a clinical trial in Phase IIl .

描述（由申请人提供）：提出了使用一次性测试条和棕榈大小的读取器开发手指粘的白血细胞（WBC）计数方法。该方法将在患者的房屋等非实验室环境中以分钟为单位估算WBC计数。用手动组装原型获得的初步数据证明了该方法的可行性。用于测量WBC计数的一种简单的护理（POC）方法将使医疗保健提供者一种监测接受化学疗法的癌症患者的便携手段。当前，没有便宜且准确的方法可用。提出的设备将通过允许医疗保健提供者在患者进行治疗之前获得WBC计数来提高化学疗法调度效率。这反过来将降低健康成本。拟议设备的POC应用程序每年有一个潜在的全球市场。在第二阶段，我们建议扩展设备，开发棕榈大小的读取器，彻底测试测定系统，并为IIL期间的临床试验做准备。