Child Health Research Career Development Award

描述(由申请人提供)：本申请寻求持续支持 爱荷华大学儿童健康研究职业发展项目。 其目的是支持以下儿科医生的研究事业发展 最近完成了分专业培训。这项提议将继续 为实验室和行政部门提供核心支持的计划 适用于许多研究项目的资源，这些研究项目涉及分子 发展生物学。其中包括识别和本地化 人类基因组中的基因，特定基因调节 基因产物的合成，基因打靶和基因转移研究基因 在组织发育中起作用。首席调查员、项目主任、 和知名的研究人员，他们资助的研究与 中国疾病控制与预防中心的焦点将作为一个咨询委员会，从 合格的新教师、儿科科学家和三名新项目获得者 任何时候都要有发展资金。每个学者都将进行调查 在一名或多名已确定的既定调查人员的指导下。每个人的遗嘱 在共享的核心实验室中执行分子生物学程序 部分由大学配套资金支持，并由 一位核心实验室主任。由该奖项支持的学者也可以花费 在各自实验室工作的其他时间段 老牌调查员。这种安排旨在提供具有成本效益的、 向学者提供质量控制的仪器和程序性能。 学者将参加讲座、研讨会和正式的研究生课程 研究伦理，以及关于分子生物学技术和策略的 发育生物学。吸引妇女和少数族裔儿科医生的措施 到研究的职业已经被纳入其中。该计划预计将 利用跨学科研究的机构基础设施 并将建立在研究职业发展的部门传统基础上。 它将促进工作效率和协作，并加快应用 基础科学的新发现，从临床到临床护理。

DESCRIPTION (provided by applicant): This application seeks ongoing support for the University of Iowa Child Health Research Career Development program. The purpose is to support the research career development of pediatricians who have recently completed subspecialty training. The proposal is to continue a program that provides core support for laboratories and administrative resources applicable to a number of research projects that address the molecular biology of development. These include the identification and localization of genes in the human genome, mechanisms by which specific genes regulate the synthesis of gene products, and gene targeting and gene transfer to study gene function in developing tissues. The Principal Investigator, Program Director, and established investigators whose funded research is closely related to the focus of the CHRCDA will act as an advisory committee to select from highly qualified new faculty pediatrician scientists three recipients of New Project Development Funds at all times. Each of the Scholars will conduct investigations under guidance of one or more identified established investigators. Each will perform molecular biologic procedures in a Shared Core Laboratory that is supported in part by university matching funds and is under the supervision of a Core Laboratory Director. Scholars supported by the award also may spend other periods of time working in the laboratories of their respective established investigators. This arrangement aims to provide cost-effective, quality-controlled instrumentation and procedure performance to Scholars. Scholars will attend lectures, seminars and formal graduate courses on research ethics, as well as on molecular biology techniques and strategies in developmental biology. Measures to attract women and minority pediatricians to research careers have been incorporated. The program is anticipated to capitalize on an institutional infrastructure of interdisciplinary research and will build upon a departmental tradition of research career development. It will promote productivity and collaboration and speed the application of new basic science discoveries to clinical to clinical care.