BASAL INSULIN DURING EXERCISE ON THE DEVELOPMENT OF HYPOGLYCEMIA

运动期间基础胰岛素对低血糖发生的影响

• 批准号: 7377074
• 负责人: EVA TSALIKIAN
• 金额: $ 0.69万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-03-01 至 2007-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7377074
• 关键词: BASAL; INSULIN; DURING; EXERCISE; DEVELOPMENT

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary objective of this study is to determine the effects of discontinuing a subject's basal rate during exercise on the glucose level during and following exercise. The study will consist of two outpatient visits each lasting approximately 7 hours with a 75-minute exercise session in the late afternoon. Assessment of changes in glucose concentrations, changes in hormone and plasma substrate concentrations during exercise will be performed. As part of the study the accuracy of a continuous glucose sensor during exercise will be assessed. The accuracy of a commercially-available home glucose meter will also be assessed.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。本研究的主要目的是确定在运动期间中断受试者的基础率对运动期间和运动后的血糖水平的影响。本研究将包括两次门诊访视，每次持续约7小时，下午晚些时候进行75分钟的运动。将评估运动期间葡萄糖浓度的变化、激素和血浆底物浓度的变化。作为研究的一部分，将评估运动期间动态葡萄糖探头的准确性。还将评估市售家用血糖仪的准确度。