NAVIGATOR CONTINUOUS GLUCOSE SENSOR TO MANAGE PEDIATRIC TYPE 1 DIABETES

用于管理儿童 1 型糖尿病的 NAVIGATOR 连续血糖传感器

基本信息

  • 批准号:
    7604846
  • 负责人:
  • 金额:
    $ 1万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2007
  • 资助国家:
    美国
  • 起止时间:
    2007-03-01 至 2007-09-16
  • 项目状态:
    已结题

项目摘要

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Resistance to frequent blood glucose monitoring is a major impediment to attaining good (lower HbA1c level) glucose control. The Diabetes Control and Complications Trial (DCCT) convincingly proved that glucose control closer-to-normal range ("tight" glycemic control) reduced the likelihood of the eye, kidney, and nerve complications of diabetes. Increasing the frequency of glucose monitoring was an important aspect of attaining improved glucose control in the DCCT. As a result of the the DCCT, many physicians have attempted to keep children and adults in very "tight" glucose control. Unfortunately, the DCCT study also showed that the incidence of severe hypoglycemia was three times higher in the intensively treated group compared with the standard treatment group. The tools to safely implement tight glycemic control were not available to the DCCT. The Navigator by TheraSense has been developed to assist in closer monitoring of glucose levels. The proper role of the Navigator in the management of type 1 diabetes in children has not been determined. We are planning a randomized clinical trial (RCT) to compare the effect on glycemic control, hypoglycemia, and quality of life of using a Navigator versus standard care. As a prelude to the RCT, we will conduct a pilot study in which subjects will use the Navigator in their home environment.
这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者(PI)可能从另一个NIH来源获得了主要资金, 因此可以在其他CRISP条目中表示。所列机构为 研究中心,而研究中心不一定是研究者所在的机构。 对频繁血糖监测的抵抗是实现良好(较低HbA 1c水平)血糖控制的主要障碍。 糖尿病控制和并发症试验(DCCT)令人信服地证明,血糖控制接近正常范围(“严格”血糖控制)降低了糖尿病的眼睛,肾脏和神经并发症的可能性。 增加血糖监测频率是DCCT中实现改善血糖控制的一个重要方面。 由于DCCT,许多医生试图让儿童和成人保持非常“严格”的血糖控制。 不幸的是,DCCT研究还显示,与标准治疗组相比,强化治疗组中严重低血糖的发生率高出3倍。 DCCT无法获得安全实施严格血糖控制的工具。 TheraSense开发的Navigator旨在帮助更密切地监测血糖水平。 Navigator在儿童1型糖尿病管理中的适当作用尚未确定。 我们正在计划一项随机临床试验(RCT),以比较使用Navigator与标准护理对血糖控制、低血糖和生活质量的影响。 作为RCT的前奏,我们将进行一项试点研究,受试者将在其家庭环境中使用Navigator。

项目成果

期刊论文数量(0)
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科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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EVA TSALIKIAN其他文献

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{{ truncateString('EVA TSALIKIAN', 18)}}的其他基金

NATURAL HISTORY STUDY OF THE DEVELOPMENT OF TYPE 1 DIABETES
1 型糖尿病发展的自然史研究
  • 批准号:
    7604849
  • 财政年份:
    2007
  • 资助金额:
    $ 1万
  • 项目类别:
REAL-TIME CONTINUOUS GLUCOSE MONITORING IN THE MANAGEMENT OF TYPE 1 DIABETES
实时连续血糖监测在 1 型糖尿病治疗中的应用
  • 批准号:
    7604925
  • 财政年份:
    2007
  • 资助金额:
    $ 1万
  • 项目类别:
ACCURACY OF CONTINUOUS GLUCOSE MONITORS IN CHILDREN WITH T1DM
T1DM 儿童连续血糖监测仪的准确性
  • 批准号:
    7604928
  • 财政年份:
    2007
  • 资助金额:
    $ 1万
  • 项目类别:
NATURAL HISTORY STUDY OF THE DEVELOPMENT OF TYPE 1 DIABETES
1 型糖尿病发展的自然史研究
  • 批准号:
    7377063
  • 财政年份:
    2006
  • 资助金额:
    $ 1万
  • 项目类别:
BASAL INSULIN DURING EXERCISE ON THE DEVELOPMENT OF HYPOGLYCEMIA
运动期间基础胰岛素对低血糖发生的影响
  • 批准号:
    7377074
  • 财政年份:
    2006
  • 资助金额:
    $ 1万
  • 项目类别:
NAVIGATOR CONTINUOUS GLUCOSE SENSOR TO MANAGE PEDIATRIC TYPE 1 DIABETES
用于管理儿童 1 型糖尿病的 NAVIGATOR 连续血糖传感器
  • 批准号:
    7377060
  • 财政年份:
    2006
  • 资助金额:
    $ 1万
  • 项目类别:
GLUCOWATCH BIOGRAPHER IN THE MANAGEMENT OF TYPE 1 DIABETES IN CHILDREN
GLUCOWATCH 传记家治疗儿童 1 型糖尿病
  • 批准号:
    7201325
  • 财政年份:
    2005
  • 资助金额:
    $ 1万
  • 项目类别:
EXERCISE ON HYPOGLYCEMIA IN CHILDREN WITH TYPE 1 DIABETES
针对 1 型糖尿病儿童低血糖的运动
  • 批准号:
    7201374
  • 财政年份:
    2005
  • 资助金额:
    $ 1万
  • 项目类别:
GlucoWatch Biographer in the Management of Type 1 DM
GlucoWatch 传记作者治疗 1 型糖尿病
  • 批准号:
    7040805
  • 财政年份:
    2004
  • 资助金额:
    $ 1万
  • 项目类别:
Glucose Monitors and Children with Type 1 Diabetes
血糖监测仪和 1 型糖尿病儿童
  • 批准号:
    7040777
  • 财政年份:
    2004
  • 资助金额:
    $ 1万
  • 项目类别:

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