Conservation genomics of endangered bird species in zoos

动物园濒危鸟类的保护基因组学

• 批准号: 2457020
• 金额: --
• 依托单位: University of East Anglia
• 依托单位国家: 英国
• 项目类别: Studentship
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=studentship-2457020
• 关键词: Conservation; genomics; endangered; bird; species

The IUCN Red List assessment of endangered species does not make use of genetic or genomic data, potentially leading to a serious underestimation of the extinction risk, and suboptimal conservation management. In addition, the Red List assessment does not make use of fitness and pedigree data collected in zoos. These data are invaluable to understand a species response to inbreeding and to inform conservation strategies in-situ. The proposed ARIES PhD project will conduct research to improve the assessment of extinction risk of bird species, and their conservation management in zoos and in the natural environment. The IUCN recognises the need to improve the Red List assessment, and they have set up the Conservation Genetics Specialist Group (CGSG). A significant advance in conservation can be made by improving the collaboration and communication between universities, the IUCN and zoos. The student will be instrumental in cementing the existing links, and conducting world-class research in genomics and conservation biology. In particular, the objectives of this PhD research project are: (1) perform whole genome sequence analysis of at least 4 bird species to estimate the current and past level of inbreeding; (2) analyse pedigree data to calculate the inbreeding coefficients of birds; (3) conduct quantitative genetic analysis to calculate the genetic load (i.e. number of lethal equivalents) of each species; (4) Use these data in a population viability analysis (PVA) with the model Vortex [3]; (5) Communicate the findings to conservation practitioners in seminars and workshops (in zoos, EAZA, IUCN), present on conferences, and write scientific articles.

世界自然保护联盟濒危物种红色名录评估没有利用遗传或基因组数据，可能导致严重低估灭绝风险，保护管理欠佳。此外，红名单评估不使用在动物园收集的健身和谱系数据。这些数据对于了解物种对近亲繁殖的反应和原位保护策略是非常宝贵的。拟议的ARIES博士项目将进行研究，以改善鸟类物种灭绝风险的评估，以及动物园和自然环境中的保护管理。世界自然保护联盟认识到有必要改进红色名录评估，并成立了保护遗传学专家组（CGSG）。通过加强大学、世界自然保护联盟和动物园之间的合作和沟通，可以在保护方面取得重大进展。学生将有助于巩固现有的联系，并在基因组学和保护生物学进行世界级的研究。本博士研究计划的主要目的是：（1）对至少4种鸟类进行全基因组序列分析，以估计其近亲繁殖的现状和过去的水平;（2）分析系谱数据，以计算鸟类的近亲繁殖系数;（3）进行定量遗传分析，以计算鸟类的遗传负荷（4）使用这些数据进行群体生存力分析（PVA），并使用模型Vortex [3];（5）在研讨会和讲习班（动物园，EAZA，IUCN）中向保护从业人员传达研究结果，出席会议，并撰写科学文章。