Lung Cancer Care Outcomes/Surveillance Consortium-Iowa
肺癌护理结果/监测联盟-爱荷华州
基本信息
- 批准号:6798663
- 负责人:
- 金额:$ 78.86万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2001
- 资助国家:美国
- 起止时间:2001-09-20 至 2006-08-31
- 项目状态:已结题
- 来源:
- 关键词:beliefcancer rehabilitation /carecontinuing educationcooperative studydata collectiondecision makinghuman subjecthuman therapy evaluationimmunomodulatorsmedical recordsneoplasm /cancer educationneoplasm /cancer immunotherapynonsmall cell lung canceroutcomes researchpatient care managementpatient oriented researchpreferencequality of lifesocial support network
项目摘要
We have assembled a team of multi-disciplinary investigators to study, on a population basis, the patterns of treatment initially and continuing for a representative sample of lung cancer patients in the state of Iowa. These patterns will be explored in terms of patient decision-making processes for short and long-term treatment, with follow-up for suitable outcomes including disease-free interval, quality-of-life measures, end of-life care and overall survivorship. Factors proposed for exploration include including patient demographic, economic and behavioral attributes, including traits such as the patient's cancer learning environment and fatalism, the influences of geographically-dispersed practitioners with varied clinical management approaches, practitioner continuing education and information sources, the application of treatments where optimal approaches are uncertain and the influence of spatial and fiscal access to care. Special features of this proposal include: a) a multi-disciplinary team of investigators including epidemiology, disease registration, biostatistics, health economics, behavioral science and thoracic oncology; b) proven ability to access approximately 2000 lung cancer patients per year and achieve long term follow-up rates of 98-99%, using the Iowa Cancer Registry (NCI SEER Program); c) the elaboration of an economics model to guide both theory and questionnaire design for patients and practitioners, and offered to understand patient decision-making and its relation to outcomes; and d) demonstrable high levels of community cooperation, from patients, cancer care practitioners and pathologists. The goal of the special study is to use Instrumental Variable (IV) techniques to assess whether patient survival rates can be increased by increasing adjuvant therapy treatment rates for early stage non-small cell lung cancer (ENSCLC) patients. If providers are accurately sorting patients by their expected treatment benefits, and only patients expected to benefit from adjuvant treatments actually receive them, we would expect that treatment benefits for patients on the extensive margin to be minimal. We hypothesize there will be little or no treatment survival benefits for patients on the ENSCLC patients provides the rationale for this study.
我们组建了一个由多学科研究者组成的团队,以人群为基础,对爱荷华州肺癌患者的代表性样本进行初步和持续治疗模式的研究。这些模式将在短期和长期治疗的患者决策过程中进行探索,并对适当的结果进行随访,包括无病间隔、生活质量测量、临终关怀和总体生存率。建议探索的因素包括患者的人口统计学、经济和行为属性,包括患者的癌症学习环境和宿命论等特征,地理上分散的从业人员使用各种临床管理方法的影响,从业人员继续教育和信息来源,最佳方法不确定的治疗方法的应用以及空间和财政获取护理的影响。该提案的特点包括:a)一个多学科的研究小组,包括流行病学、疾病登记、生物统计学、卫生经济学、行为科学和胸部肿瘤学;b)使用爱荷华州癌症登记处(NCI SEER计划),每年可接触约2000名肺癌患者,并实现98-99%的长期随访率;C)建立经济学模型,为患者和从业者提供理论和问卷设计指导,并提供理解患者决策及其与结果的关系;d)来自患者、癌症护理从业人员和病理学家的高水平社区合作。这项特殊研究的目的是使用工具变量(IV)技术来评估是否可以通过提高早期非小细胞肺癌(ENSCLC)患者的辅助治疗率来提高患者的生存率。如果医疗服务提供者根据预期的治疗效果准确地对患者进行分类,并且只有预期从辅助治疗中受益的患者才真正接受了辅助治疗,那么我们可以预期,在广泛的范围内,患者的治疗效果是最小的。我们假设对于接受ENSCLC的患者来说,治疗后的生存获益很少或没有,这为本研究提供了基本原理。
项目成果
期刊论文数量(0)
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Robert Bruce Wallace其他文献
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{{ truncateString('Robert Bruce Wallace', 18)}}的其他基金
Lung Cancer Care Outcomes/Surveillance Consortium-Iowa
肺癌护理结果/监测联盟-爱荷华州
- 批准号:
6947878 - 财政年份:2001
- 资助金额:
$ 78.86万 - 项目类别:
Lung Cancer Care Outcomes/Surveillance Consortium--Iowa
肺癌护理结果/监测联盟——爱荷华州
- 批准号:
6413870 - 财政年份:2001
- 资助金额:
$ 78.86万 - 项目类别: