Studies of Prosody...Autistic Spectrum Disorders

韵律研究...自闭症谱系障碍

• 批准号: 6846340
• 负责人: RHEA PAUL
• 金额: $ 9.81万
• 依托单位: SOUTHERN CONNECTICUT STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-01-23 至 2008-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6846340
• 关键词: Williams syndrome; adolescence (12-20); autism; child behavior; clinical research; communication disorders; functional magnetic resonance imaging; human subject; method development; neuroimaging; patient oriented research; performance; robotics; sensory signal detection; speech disorders; speech recognition; verbal behavior

DESCRIPTION (provided by applicant): The proposed project will provide 50% salary support for five years to release the applicant from teaching and other faculty responsibilities at Southern Connecticut State University and allow her to work on a series of patient-oriented research studies and to mentor beginning speech-language clinicians at the Yale Child Study Center. The candidate is a productive researcher (60 papers in refereed journals) who has, for the past 16 years, been teaching at state universities with heavy teaching loads. This award would provide her with the opportunity to engage in focused research and mentoring activities in a patient-oriented clinical research environment. The Yale Child Study Center has been active in both research and clinical care of children with autism for more than 20 years. The Center provides both a source of subjects for research and a multidisciplinary clinic that serves large numbers of these children and their families, as well as the opportunities for collaborations with scientists from a broad range of backgrounds. The candidate's long-term goals in this project are: 1) to increase her knowledge and skills in three areas in which specific collaborators have been proposed--instrumental speech analysis and signal detection, neuroimaging, and robotics; and 2) to devote more time and attention to patient-oriented research and clinical mentoring. The research career development plan proposed here will result in maximizing the candidate's opportunity to contribute to knowledge and practice in the field of communication disorders in autism. The research plan for this project involves three studies: 1) the study of the production of prosody in grammatical and pragmatic/affective contexts in high functioning individuals with autistic spectrum disorders (ASDs) and appropriate contrast groups, using instrumental analysis and signal detection methodologies, both to better detail prosodic abilities and to work toward the development of a prosodic intervention protocol; 2) the study of the perception of prosody in grammatical and pragmatic/affective contexts in high functioning individuals with ASDs and appropriate contrast groups, both to better detail their abilities and to work toward the development of a protocol that can be tested via functional magnetic resonance imaging for future studies of the neural organization of prosody and to investigate differences in processing strategies between typical subjects and those with ASDS; and 3) the development of a prosodic intervention program with a robotic generalization training phase, to be tested against a traditional intervention program.

描述(由申请者提供)：拟议的项目将提供50%的工资支持，为期五年，以免除申请者在南康涅狄格州立大学的教学和其他教职职责，并允许她从事一系列以患者为导向的研究，并指导耶鲁儿童研究中心的初级语言临床医生。这位候选人是一位多产的研究人员(在被推荐的期刊上发表了60篇论文)，在过去的16年里，他一直在教学负担沉重的州立大学任教。这一奖项将为她提供在以患者为中心的临床研究环境中从事重点研究和指导活动的机会。20多年来，耶鲁儿童研究中心一直活跃在自闭症儿童的研究和临床护理方面。该中心既提供研究课题的来源，也提供为大量儿童及其家人服务的多学科诊所，并提供与来自广泛背景的科学家合作的机会。候选人在这个项目中的长期目标是：1)在已提出的三个特定合作者的领域增加她的知识和技能--工具语音分析和信号检测、神经成像和机器人；2)将更多的时间和精力投入到以患者为导向的研究和临床指导上。这里提出的研究职业发展计划将使候选人有最大的机会为自闭症沟通障碍领域的知识和实践做出贡献。该项目的研究计划包括三项研究：1)使用仪器分析和信号检测方法，研究高功能自闭症谱系障碍(ASD)患者和适当的对照组在语法和语用/情感语境中的韵律产生，以更好地详细说明韵律能力，并致力于制定韵律干预方案；2)研究高功能自闭症患者和适当对照组在语法和语用/情感语境中对韵律的感知，以更好地详细说明他们的能力，并致力于开发一种可通过功能磁共振成像测试的方案，用于未来韵律神经组织的研究，并调查典型受试者和自闭症患者在处理策略上的差异；以及3)开发带有机器人概括训练阶段的韵律干预程序，以与传统干预程序进行测试。