Midcareer Development in Nonpharmacologic Analgesia

非药物镇痛的职业中期发展

• 批准号: 6881263
• 负责人: ELVIRA Valentina LANG-ANDERSON
• 金额: $ 13.15万
• 依托单位: BETH ISRAEL DEACONESS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-01 至 2007-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6881263
• 关键词: alternative medicine; analgesia; anxiety; biopsy; blood pressure; breast neoplasm /cancer diagnosis; breast surgery; career; clinical research; cognition; cortisol; female; heart rate; human subject; hypnosis; information dissemination; mind control; pain; patient oriented research; physiologic stressor; psychological stressor; questionnaires; relaxation; saliva

Alternative medical methods enjoy broad acceptance by the public, but are rarely integrated into conventional medical practice. In the largest prospective randomized study of its kind, published by the Lancet, the candidate showed that non-pharmacologic analgesia in the form of self- hypnotic relaxation during invasive medical procedures significantly reduces patients' pain anxiety, drug use, number of complications, hemodynamic instability, and procedure time. This results in substantial resource savings. The immediate goal of the candidate is to expand and validate this concept of integrated alternative/conventional health care delivery across disciplines. The long-term goal is the successful transition from scientific investigation to general implementation of acute non-pharmacologic analgesia in clinical settings. The candidate is uniquely situated to achieve the state goals: A strong foundation in laboratory and clinical research as well as her position as Director of International Radiology provides her the necessary credibility to promote and implement mind body intervention during invasive medical procedures. Her acceptance by both conventional medical and mind-body oriented professional societies permit integration of her methods into both communities. The candidate's RO1 and DOD funding focuses on assessment on non-pharmacologic analgesia during invasive vascular procedures and during large core breast biopsy. Under the proposed mid-career award, she will (1) acquire authoritative expertise in the introduction and quality assessment of non- pharmacologic analgesia techniques in conventional clinical settings (2) assume a key role in the newly established Harvard-wide Division for Research and Education and Complementary and Integrative Medical Therapies, and (3) mentor the next generation of researchers and practitioners in this field. Towards these aims the candidate will acquire additional research skills in educational technology, quality assessment, and web-based dissemination; acquire expertise in additional complementary and alternative therapies; and will make available to other researchers data banks, ideas, experience and patients in fully monitored clinical environment. She will assume primary mentoring responsibility for a total of 15 beginning clinical researchers. Upon completion, the candidate will have established herself as an authority in the introduction and quality assessment of combined alternative/conventional medical practices. The mentoring of beginning clinical researchers will have contributed towards fostering a self- sustaining mode of integrated practice in the future.

替代医疗方法受到公众的广泛接受，但很少融入传统医疗实践。在《柳叶刀》发表的同类最大的前瞻性随机研究中，候选者表明，在侵入性医疗手术期间以自我催眠放松形式进行的非药物镇痛可显着减少患者的疼痛焦虑、药物使用、并发症数量、血流动力学不稳定和手术时间。这会节省大量资源。候选人的近期目标是扩展和验证跨学科综合替代/传统医疗保健提供的概念。长期目标是从科学研究成功过渡到临床环境中急性非药物镇痛的普遍实施。该候选人在实现国家目标方面具有独特的优势：实验室和临床研究的坚实基础以及她作为国际放射科主任的职位为她在侵入性医疗程序中促进和实施身心干预提供了必要的可信度。她被传统医学和以身心为导向的专业协会所接受，这使得她的方法能够融入这两个社区。该候选人的 RO1 和 DOD 资助重点用于评估侵入性血管手术和大核心乳腺活检期间的非药物镇痛。根据拟议的职业中期奖项，她将（1）获得在传统临床环境中非药物镇痛技术的介绍和质量评估方面的权威专业知识（2）在新成立的哈佛大学研究与教育以及补充和综合医学治疗部门中发挥关键作用，以及（3）指导该领域的下一代研究人员和从业者。为了实现这些目标，候选人将获得教育技术、质量评估和网络传播方面的额外研究技能；获得额外补充和替代疗法的专业知识；并将在完全监控的临床环境中向其他研究人员提供数据库、想法、经验和患者。她将承担对总共 15 名初级临床研究人员的主要指导责任。完成后，候选人将确立自己在替代/传统组合医疗实践的介绍和质量评估方面的权威。对初级临床研究人员的指导将有助于在未来培养一种自我维持的综合实践模式。