BIOLOGICAL & PHYSIOLOGICAL DETERMINANTS OF BEHAVIOR
BIOLOGICAL & PHYSIOLOGICAL DETERMINANTS OF BEHAVIOR
批准号:
6888537
负责人:
Bruce S. McEwen
金额:
$29.62万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1991
资助国家:
美国
项目状态:
已结题
起止时间:
1991-09-30 至 2006-10-31
中文摘要
超出所提供的空间。 我们的培训计划的目标是在大脑和行为的研究中提供广泛而全面的培训,这超过了任何一个单独的受训者在一个实验室中获得的。学员和导师之间的互动使科学体验更加愉快,并为学员创造了超越任何一个人或实验室所能提供的协作互动和学习体验。我们的培训补助金的过去历史提供了合作与合作的基础,将在此应用程序中进一步加强。洛克菲勒大学的六个实验室参与了这个培训计划,以及这些实验室内的教职员工。该计划的关键组成部分包括系统地向学员介绍我们的6个实验室所提供的服务,从而促进合作和学习新技能。6名实验室负责人担任指导委员会,负责挑选受训人员和评估进展情况,并定期与受训人员会面,讨论科学问题和满足受训人员的需求。为了补充实验室经验,我们打算通过课程和辅导来补充受训者以前的经验,并促进“生存技能”的发展,包括书面和口头陈述,这将使受训者能够更好地作为一名独立的科学家发挥作用。该培训计划的科学目的是提供跨学科的博士后培训和研究经验的各种行为过程的基本生物和心理决定因素。该计划的一个中心重点是了解环境与遗传结构相互作用的方式,并通过激素,神经递质和药物等化学信使改变大脑的结构和功能。行为过程包括与繁殖和领土保卫有关的季节性和周期性行为(包括特别是鸟鸣);动机状态;压力对大脑的影响;学习和记忆的基本过程;以及精神分裂症、强迫症、抑郁症和阿尔茨海默病等异常状态。培训计划尤其重要,为学员提供广泛而丰富的学习经验,帮助他们为独立的职业生涯做好准备。我们提出的培训计划是一个正在进行的计划,这是在其21年的延续。性能现场=
英文摘要
EXCEED THE SPACE PROVIDED. The goal of our training program is to provide broad and comprehensive training in the study of brain and behavior that surpasses what any individual trainee would obtain in a single laboratory. The interactions between trainees and preceptors makes the scientific experience more enjoyable and creates collaborative interactions and learning experiences for the trainees that go beyond what any oneindividual or laboratory can provide. The past history of our training grant has provided a basis for collaboration and cooperation that will be further enhanced in this application.Six laboratories at The Rockefeller University are involved in this training program, together with faculty members within these laboratories. Key components of the plan involve introducing trainees systematically to what our 6 laboratories have to offer, leading to the facilitation of collaborations and learning of new skills. The 6 lab heads act as a steering committee for the selection of trainees and assessment of progress, as well as meeting with the trainees on a regular basis to discuss science and deal with the needs of the trainees. To supplement laboratory experiences we intend to supplement the trainee's prior experience through courses and tutorials, and to facilitate development of "survival skills", involving written and oral presentation, that will enable the trainee to function better as an independent scientist. The scientific aim of this training program is to provide interdisciplinary postdoctoral training and research experience on the basic biological and psychological determinants of a variety of behavioral processes. A central focus of this program is understanding the ways in which the environment interacts with the genetic constitution and modifies the structure and function of the brain through chemical messengers such as hormones, neurotransmitters and drugs. Behavioral processes include seasonal and cyclical behaviors related to reproductionand defense of territory (including and especially bird song) ; motivational states; the impact of stress on the brain; fundamental processes underlying learning and memory; and abnormal states such as schizophrenia, obsessive compulsive disorder, depressive illness and Alzheimer's disease. The training program is particularly important in providing trainees with a broad and rich learning experience, helping to prepare them for an independent career. Our proposed training program is a continuation of an ongoing program which is in its 21 year. PERFORMANCE SITE ========================================Section End===========================================
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Sex differences in response to discrete estradiol injections.
对离散雌二醇注射的反应存在性别差异。
DOI:
10.1016/0018-506x(86)90006-1
发表时间:
1986
期刊:
Hormones and behavior
影响因子:
3.5
作者:
[Moreines,J, McEwen,B, Pfaff,D]
通讯作者:
Pfaff,D
Expression of salt hunger in hypophysectomized rats.
垂体切除大鼠的盐饥饿表达。
DOI:
10.1159/000125261
发表时间:
1989
期刊:
Neuroendocrinology
影响因子:
4.1
作者:
[Schulkin,J, Angulo,J, Sakai,R, McEwen,BS]
通讯作者:
McEwen,BS
Early estrogen-induced nuclear changes in rat hypothalamic ventromedial neurons: an ultrastructural and morphometric analysis.
大鼠下丘脑腹内侧神经元早期雌激素诱导的核变化:超微结构和形态测量分析。
DOI:
10.1002/cne.902390302
发表时间:
1985
期刊:
The Journal of comparative neurology
影响因子:
--
作者:
[Jones,KJ, Pfaff,DW, McEwen,BS]
通讯作者:
McEwen,BS
Hormonal control of sexual behavior in the female rat: molecular, cellular and neurochemical studies.
雌性大鼠性行为的激素控制:分子、细胞和神经化学研究。
DOI:
10.1095/biolreprod36.1.37
发表时间:
1987
期刊:
Biology of reproduction
影响因子:
3.6
作者:
[McEwen,BS, Jones,KJ, Pfaff,DW]
通讯作者:
Pfaff,DW
LHRH messenger RNA in neurons in the intact and castrate male rat forebrain, studied by in situ hybridization.
通过原位杂交研究完整和去势雄性大鼠前脑神经元中的 LHRH 信使 RNA。
DOI:
10.1007/bf00269459
发表时间:
1987
期刊:
Experimental brain research
影响因子:
2
作者:
[Rothfeld,JM, Hejtmancik,JF, Conn,PM, Pfaff,DW]
通讯作者:
Pfaff,DW
共 18 条
ESTROGEN-REGULATED PLASTICITY OF HIPPOCAMPAL NEURONS
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批准号:6869954
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项目类别:
-
资助金额:$21.64万
-
财政年份:2005
-
负责人:Bruce S. McEwen
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依托单位:
ESTROGEN REGULATED PLASTICITY OF HIPPOCAMPAL NEURONS
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批准号:6299414
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项目类别:
-
资助金额:$32.12万
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财政年份:2000
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负责人:Bruce S. McEwen
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依托单位:
NEUROHORMONAL MECHANISMS OF SALT APPETITE
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批准号:6353114
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项目类别:
-
资助金额:$21.63万
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财政年份:2000
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负责人:Bruce S. McEwen
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依托单位:
FEAR, STRESS AND HIPPOCAMPAL PLASTICITY
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批准号:6336698
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项目类别:
-
资助金额:$29.64万
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财政年份:2000
-
负责人:Bruce S. McEwen
-
依托单位:
FEAR, STRESS AND HIPPOCAMPAL PLASTICITY
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批准号:6232839
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项目类别:
-
资助金额:$29.64万
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财政年份:1999
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负责人:Bruce S. McEwen
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依托单位:
NEUROHORMONAL MECHANISMS OF SALT APPETITE
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批准号:6204817
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项目类别:
-
资助金额:$21.63万
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财政年份:1999
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负责人:Bruce S. McEwen
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依托单位:
ESTROGEN REGULATED PLASTICITY OF HIPPOCAMPAL NEURONS
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批准号:6098856
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项目类别:
-
资助金额:$32.12万
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财政年份:1999
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负责人:Bruce S. McEwen
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依托单位:
NEUROHORMONAL MECHANISMS OF SALT APPETITE
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批准号:6111420
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项目类别:
-
资助金额:$21.63万
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财政年份:1998
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负责人:Bruce S. McEwen
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依托单位:
NEUROHORMONAL MECHANISMS OF SALT APPETITE
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批准号:6243038
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项目类别:
-
资助金额:$20.78万
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财政年份:1997
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负责人:Bruce S. McEwen
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依托单位:
MINORITY HIGH SCHOOL STUDENT RESEARCH APPRENTICE PROGRAM
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批准号:2282785
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项目类别:
-
资助金额:$2.6万
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财政年份:1992
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负责人:Bruce S. McEwen
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依托单位:
MINORITY HIGH SCHOOL STUDENT RESEARCH APPRENTICE PROGRAM
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批准号:3513080
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项目类别:
-
资助金额:$3.7万
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财政年份:1992
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负责人:Bruce S. McEwen
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依托单位:
MINORITY HIGH SCHOOL STUDENT RESEARCH APPRENTICE PROGRAM
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批准号:3513079
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项目类别:
-
资助金额:$3.5万
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财政年份:1992
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负责人:Bruce S. McEwen
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依托单位:
BIOLOGICAL & PHYSIOLOGICAL DETERMINANTS OF BEHAVIOR
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批准号:6538397
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项目类别:
-
资助金额:$26.14万
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财政年份:1991
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负责人:Bruce S. McEwen
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依托单位:
STRESS, ADRENAL STEROIDS AND THE BRAIN
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批准号:6538583
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项目类别:
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资助金额:$31.52万
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财政年份:1991
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负责人:Bruce S. McEwen
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依托单位:
STRESS, ADRENAL STEROIDS AND THE BRAIN
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批准号:2245148
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项目类别:
-
资助金额:$18.15万
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财政年份:1991
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负责人:Bruce S. McEwen
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依托单位:
STRESS, ADRENAL STEROIDS AND THE BRAIN
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批准号:2245150
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项目类别:
-
资助金额:$19.17万
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财政年份:1991
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负责人:Bruce S. McEwen
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依托单位:
STRESS, ADRENAL STEROIDS AND THE BRAIN
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批准号:6608577
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项目类别:
-
资助金额:$31.95万
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财政年份:1991
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负责人:Bruce S. McEwen
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依托单位:
Stress, Adrenal Steroids and the Brain
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批准号:8815200
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项目类别:
-
资助金额:$50.13万
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财政年份:1991
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负责人:Bruce S. McEwen
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依托单位:
STRESS, ADRENAL STEROIDS AND THE BRAIN
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批准号:2245151
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项目类别:
-
资助金额:$8.1万
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财政年份:1991
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负责人:Bruce S. McEwen
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依托单位:
STRESS, ADRENAL STEROIDS AND THE BRAIN
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批准号:3379831
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项目类别:
-
资助金额:$21.81万
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财政年份:1991
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负责人:Bruce S. McEwen
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依托单位:
海外基金