Clinical Pharmacology Training Program

描述(由申请人提供)： 这是一项新的倡议，旨在支持约翰霍普金斯大学四年临床药理学培训计划中的医学博士后研究员。它旨在解决公认的、经过严格培训的内科科学家的短缺问题，这些科学家在人体上进行实践研究，特别是在临床药理学领域。该计划的中心是临床药理学部门，这是医学院医学系和药理学和分子科学系的一个联合单位。最近两个上级部门和该部门本身的领导层变动提供了令人兴奋的新机会，使直接将分子科学和临床科学联系起来的培训计划正规化。拟议的四年计划包括一年的临床药理学核心课程(课程作业和三次研究轮换)，然后是三年的临床调查博士研究生培训计划的论文研究。论文项目将包括分子和临床组件，这是一个在该部门过去和现在的学员中成功使用的模型。基于现有部门教职员工的集体专业知识，研究可能集中在抗感染药物的某些方面，新的重点是抗寄生虫剂。每名学员将有一名初级导师，负责监督研究项目的临床方面，并在适当时辅以一名具有基础科学专业知识的共同导师。参与的教师不仅包括目前在临床药理学分部的那些人，而且还包括一个被选择来反映正在进行的或可预见的研究合作和重要的教学协会的小组。该计划将受益于咨询委员会的建议和监督，咨询委员会由来自约翰·霍普金斯大学内外的杰出临床医生和科学家组成。该项目的毕业生将拥有从事基础和临床药理学研究的独立职业的技能和知识。

DESCRIPTION (provided by applicant): This is a new initiative to support MD postdoctoral fellows in a four year clinical pharmacology training program at Johns Hopkins. It is designed to address the widely-recognized shortage of rigorously trained physician scientists who conduct hands-on studies in humans, particularly in the area of clinical pharmacology. The program is centered in the Division of Clinical Pharmacology, a unit jointly under the Department of Medicine and the Department of Pharmacology and Molecular Sciences, in the School of Medicine. Recent leadership changes in both parent Departments and in the Division itself afford exciting new opportunities to formalize a training program that directly links molecular and clinical sciences. The proposed four year program includes a one year core curriculum in clinical pharmacology (coursework plus three research rotations) followed by three years of thesis research in the PHD-granting Graduate Training Program in Clinical Investigation. Thesis projects will include a molecular as well as a clinical component, a model used successfully with past and current trainees in the Division. Based on the collective expertise of the existing Division faculty, research is likely to focus on some aspect of anti-infective drugs, with a new emphasis on anti-parasitic agents. Each trainee will have a Primary' Mentor who will oversee the clinical aspects of the research project, complemented when appropriate by a Co-Mentor with expertise in basic science. The participating faculty includes not only those currently in the Division of Clinical Pharmacology but also a group chosen to reflect ongoing or foreseeable research collaborations and important teaching associations. The program will benefit from the advice and oversight of an Advisory Board comprised of distinguished clinician-scientists from within and outside of Johns Hopkins. Graduates from this program will have the skills and knowledge to undertake an independent career that features research in both basic and clinical pharmacology.