Training in Basic and Clinical Pharmacology in Pregnancy

妊娠期基础和临床药理学培训

• 批准号: 8459949
• 负责人: STEVE N CARITIS
• 金额: $ 13.34万
• 依托单位: MAGEE-WOMEN'S RES INST AND FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-05-01 至 2017-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8459949
• 关键词: Clinical Pharmacology; Pregnancy; Training

DESCRIPTION (provided by applicant): The University of Pittsburgh training grant "Basic and Translational Training in Obstetric- Fetal Pharmacology" aims to provide trainees essential classroom education as well as the research tools and clinical exposures necessary to bridge the longstanding impediments to meaningful and scientifically sound research in perinatal pharmacology. Both clinical and non-clinical research scientists who are committed to a research career and have a particular interest in the study of pregnant women and their fetuses will be recruited. Through a combination of targeted coursework, clinical exposure to pregnant women and research training, trainees will gain the fundamental tools required to carry out research related to pregnancy. This training will be linked to ongoing research in obstetrical pharmacology by research mentors and will lead to trainee-initiated research aimed at developing an area of research focus. The specific aims of our proposal are: 1) To consolidate the extensive resources at the University of Pittsburgh in basic sciences, epidemiology, pharmacology, women's health clinical research and education into a distinct training program in Obstetrical - Fetal pharmacology. 2) To recruit highly motivated, research-oriented, academically successful individuals for training in Obstetric- Fetal pharmacology. 3) To develop these recruits into individuals with sufficient skills to perform independent basic, translational and clinical research in maternal and fetal pharmacology and therapeutics. Many of the components for a successful program in Obstetrical-Fetal pharmacology already exist at the University of Pittsburgh. Collaborative research in perinatal pharmacology by the two investigators began over 26 years ago and is still robust culminating in our selection as one of four sites in the Obstetrical-Fetal Pharmacology Research Units (OPRU) Network. Basic, clinical and translational research focused on pregnancy at the University of Pittsburgh is broad based, extensive and well funded. Training of post-doctoral fellows is likewise extensive, well established, and highly successful. Fellowships in Maternal- Fetal Medicine, perinatal biology, pharmacology, genetics, reproductive infectious diseases already exist. The focus of the current proposal is to unify the extensive resources at the University of Pittsburgh under a single training program that emphasizes a multidisciplinary approach to training individuals in obstetric pharmacology. We will recruit and train 3 clinical and 5 non-clinical post-doctoral candidates through a combination of targeted coursework in pharmacology and clinical research methodologies, clinical practicums and laboratory work with experienced clinical, basic and translational researchers in obstetrical pharmacology.

描述(由申请人提供)：匹兹堡大学培训基金“产科-胎儿药理学基础和转译培训”旨在为学员提供基本的课堂教育以及必要的研究工具和临床经验，以消除围产期药理学研究中长期存在的有意义和科学合理的研究障碍。致力于研究事业并对孕妇及其胎儿的研究特别感兴趣的临床和非临床研究科学家将被招募。通过有针对性的课程作业、与孕妇的临床接触和研究培训相结合，受训者将获得开展与怀孕有关的研究所需的基本工具。这项培训将与研究导师正在进行的产科药理学研究联系起来，并将导致学员发起的研究，旨在发展一个研究重点领域。我们建议的具体目标是：1)将匹兹堡大学在基础科学、流行病学、药理学、妇女健康临床研究和教育方面的广泛资源整合到一个独特的产科-胎儿药理学培训计划中。2)招募积极进取、以研究为导向、在学术上取得成功的个人参加产科-胎儿药理学培训。3)将这些新兵培养成具有足够技能的人，以便在母婴药理学和治疗学方面进行独立的基础、翻译和临床研究。匹兹堡大学已经具备了一个成功的产科-胎儿药理学项目的许多要素。这两位研究人员在围产期药理学方面的合作研究始于26年前，目前仍在蓬勃发展，最终我们被选为产科-胎儿药理学研究单位(OPRU)网络的四个站点之一。匹兹堡大学以怀孕为重点的基础、临床和转化性研究基础广泛、范围广泛，资金充足。对博士后研究员的培训也同样广泛、完善和成功。母婴医学、围产期生物学、药理学、遗传学、生殖传染病方面的奖学金已经存在。当前提案的重点是将匹兹堡大学的广泛资源统一在一个单一的培训计划下，该计划强调以多学科的方法培训个人产科药理学。我们将招聘和培训3名临床博士后和5名非临床博士后候选人，通过有针对性的药理学和临床研究方法学课程、临床实践和与产科药理学经验丰富的临床、基础和翻译研究人员的实验室工作相结合的方式。