CHEMISTRY-BIOLOGY INTERFACE PREDOCTORAL TRAINING GRANTS

化学-生物学接口博士前培训补助金

基本信息

项目摘要

EXCEED THE SPACE PROVIDED. In this proposal, we request a second renewal of our Chemistry-Biology Interface (CBI) Predoctoral Training Grant. In 1995 we launched a new interdisciplinary training program at the University of Massachusetts that built on existing strengths and formalized the faculty's commitment to collaboration between the physical and life sciences. We implemented a CBI curriculum that meshed with the requirements of the three participating graduate programs, Chemistry, Molecular & Cellular Biology, and Polymer Science & Engineering, yet enabled students with either chemical or biological backgrounds to supplement training in their home discipline with training in the complementary discipline. During the current funding period, our CBI Training Program has grown substantially: the number of participating departments has grown from 3 to 4, the number of CBI Training Faculty has grown from 16 to 19 and most notably, the number of formally affiliated students has increased from 14 to 61. The addition of Chemical Engineering builds our strengths in quantitative training and in biomaterials, and adds new opportunities in bioengineering. We anticipate continued growth of our CBI Program as additional departments, notably Physics and Computer Science, move into CBI-related areas. The CBI Program currently provides NIH support for six predoctoral students, and a University match supports one additional graduate student working at the chemistry-biology interface. To continue to foster the growing strength of the CBI program as it expands into new disciplines and trains increasing numbers of students, we request a modest increase in the number of NIH-funded Traineeships in years 3-5 of the of the grant period. The interdisciplinary training we provide is exemplified by the development of a new "Drug Design" course that is now an intergral part of the CBI curriculum. In this popular course, students are provided with background lectures in chemistry and biology to bring them to a common ground, followed by weekly seminars by speakers from the pharmaceutical industry to introduce students to the full range of topics in chemistry and biology that are critical for successful design and development of new drugs. With this type of training in the methods and intellectual framework of both chemistry and biology, our CBI graduates are equipped to pose and solve significant biomedical questions in their future work. PERFORMANCE SITE ========================================Section End===========================================
超出所提供的空间。在此提案中,我们要求第二次更新我们的化学-生物学界面(CBI)博士前培训补助金。1995年,我们在马萨诸塞大学启动了一个新的跨学科培训项目,该项目建立在现有优势的基础上,并正式确立了教员对物理科学和生命科学之间合作的承诺。我们实施了一套CBI课程,与三个参与的研究生项目——化学、分子与细胞生物学、聚合物科学与工程——的要求相匹配,使具有化学或生物学背景的学生能够在补充学科的基础上补充本学科的训练。在目前的资助期内,我们的CBI培训项目有了很大的发展:参与的部门从3个增加到4个,CBI培训学院的数量从16个增加到19个,最值得注意的是,正式附属学生的数量从14个增加到61个。化学工程的加入建立了我们在定量培训和生物材料方面的优势,并为生物工程增加了新的机会。随着物理系和计算机科学系进入CBI相关领域,我们预计CBI项目将继续增长。CBI项目目前为六名博士预科生提供NIH支持,一所大学的匹配项目支持一名在化学-生物学界面工作的研究生。随着CBI项目扩展到新的学科和培养越来越多的学生,为了继续培养CBI项目不断增长的实力,我们要求在资助期的第3-5年适度增加nih资助的培训名额。我们提供的跨学科培训以开发新的“药物设计”课程为例,该课程现已成为CBI课程的一个组成部分。在这门受欢迎的课程中,学生们将获得化学和生物学的背景讲座,以使他们达成共识,然后每周由制药业的演讲者举办研讨会,向学生介绍化学和生物学的所有主题,这些主题对成功设计和开发新药至关重要。通过这种化学和生物学方法和知识框架的培训,我们的CBI毕业生有能力在未来的工作中提出和解决重要的生物医学问题。网站性能 ======================================== 节结束 ===========================================

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Lynmarie K. Thompson其他文献

Investigating the Role of Receptor Clustering and Dynamics in Transmembrane Signaling by Functional Arrays of Bacterial Chemoreceptors
  • DOI:
    10.1016/j.bpj.2008.12.3573
  • 发表时间:
    2009-02-01
  • 期刊:
  • 影响因子:
  • 作者:
    Fe C. Consolacion;Daniel J. Fowler;Seena S. Koshy;Robert M. Weis;Lynmarie K. Thompson
  • 通讯作者:
    Lynmarie K. Thompson
Investigating the Functional Dynamics of Bacterial Chemoreceptors Using Hydrogen Exchange Mass Spectrometry
  • DOI:
    10.1016/j.bpj.2010.12.2470
  • 发表时间:
    2011-02-02
  • 期刊:
  • 影响因子:
  • 作者:
    Seena S. Koshy;Stephen J. Eyles;Robert M. Weis;Lynmarie K. Thompson
  • 通讯作者:
    Lynmarie K. Thompson
Regulation of ATP affinity to the bacterial chemotaxis kinase CheA
  • DOI:
    10.1016/j.bpj.2023.11.2083
  • 发表时间:
    2024-02-08
  • 期刊:
  • 影响因子:
  • 作者:
    Katherine Wahlbeck;Jasna Fejzo;Lynmarie K. Thompson
  • 通讯作者:
    Lynmarie K. Thompson
HDX-MS indicates that stabilization of the catalytic domain is key to controlling kinase activity of CheA in bacterial chemotaxis
  • DOI:
    10.1016/j.bpj.2021.11.1092
  • 发表时间:
    2022-02-11
  • 期刊:
  • 影响因子:
  • 作者:
    Thomas Tran;Aruni Karunanayake Mudiyanselage;Stephen J. Eyles;Lynmarie K. Thompson
  • 通讯作者:
    Lynmarie K. Thompson
Determining the role of the coupling protein CheW in signal transduction of chemoreceptor complexes using solid-state NMR
  • DOI:
    10.1016/j.bpj.2021.11.1103
  • 发表时间:
    2022-02-11
  • 期刊:
  • 影响因子:
  • 作者:
    Jessica Allen;Lynmarie K. Thompson
  • 通讯作者:
    Lynmarie K. Thompson

Lynmarie K. Thompson的其他文献

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{{ truncateString('Lynmarie K. Thompson', 18)}}的其他基金

Assembly and Function of Bacterial Chemotaxis Receptor Signaling Complexes
细菌趋化性受体信号复合物的组装和功能
  • 批准号:
    10655555
  • 财政年份:
    2017
  • 资助金额:
    $ 0.52万
  • 项目类别:
Assembly and Function of Bacterial Chemotaxis Receptor Signaling Complexes
细菌趋化性受体信号复合物的组装和功能
  • 批准号:
    10580973
  • 财政年份:
    2017
  • 资助金额:
    $ 0.52万
  • 项目类别:
Assembly and Function of Bacterial Chemotaxis Receptor Signaling Complexes
细菌趋化性受体信号复合物的组装和功能
  • 批准号:
    10435447
  • 财政年份:
    2017
  • 资助金额:
    $ 0.52万
  • 项目类别:
Assembly and Function of Bacterial Chemotaxis Receptor Signaling Complexes
细菌趋化性受体信号复合物的组装和功能
  • 批准号:
    8452115
  • 财政年份:
    2010
  • 资助金额:
    $ 0.52万
  • 项目类别:
Assembly and Function of Bacterial Chemotaxis Receptor Signaling Complexes
细菌趋化性受体信号复合物的组装和功能
  • 批准号:
    8054260
  • 财政年份:
    2010
  • 资助金额:
    $ 0.52万
  • 项目类别:
Assembly and Function of Bacterial Chemotaxis Receptor Signaling Complexes
细菌趋化性受体信号复合物的组装和功能
  • 批准号:
    8245792
  • 财政年份:
    2010
  • 资助金额:
    $ 0.52万
  • 项目类别:
Assembly and Function of Bacterial Chemotaxis Receptor Signaling Complexes
细菌趋化性受体信号复合物的组装和功能
  • 批准号:
    7783625
  • 财政年份:
    2010
  • 资助金额:
    $ 0.52万
  • 项目类别:
Chemistry-Biology Interface Predoctoral Training Grant
化学-生物界面博士前培训补助金
  • 批准号:
    7887049
  • 财政年份:
    2009
  • 资助金额:
    $ 0.52万
  • 项目类别:
Chemistry Biology Interface Predoctoral Training Grant
化学生物学接口博士前培训补助金
  • 批准号:
    8017856
  • 财政年份:
    1995
  • 资助金额:
    $ 0.52万
  • 项目类别:
Chemistry Biology Interface Predoctoral Training Grant
化学生物学接口博士前培训补助金
  • 批准号:
    8894513
  • 财政年份:
    1995
  • 资助金额:
    $ 0.52万
  • 项目类别:

相似国自然基金

Journal of Integrative Plant Biology
  • 批准号:
    31024801
  • 批准年份:
    2010
  • 资助金额:
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  • 项目类别:
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  • 批准号:
    2348203
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    2024
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    10627441
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  • 批准号:
    10628150
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    2023
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New Molecules, Methods, and Platforms at the Interface of Organic Chemistry and Chemical Biology
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  • 批准号:
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  • 财政年份:
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Chemistry-Biochemistry-Biology Interface (CBBI) Program at Notre Dame
圣母大学化学-生物化学-生物学接口(CBBI)项目
  • 批准号:
    10624273
  • 财政年份:
    2022
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    $ 0.52万
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    10596163
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    $ 0.52万
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  • 批准号:
    10626778
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    2022
  • 资助金额:
    $ 0.52万
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REU Site: SURFing the Interface between Chemistry and Biology
REU 网站:探索化学与生物学之间的界面
  • 批准号:
    2229342
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  • 批准号:
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NIH Training Grant in Chemistry-Biology Interface
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  • 批准号:
    10410907
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