Group Treatment for Depression in Heart Failure

心力衰竭抑郁症的团体治疗

• 批准号: 6844352
• 负责人: MICHAEL A FRIEDMAN
• 金额: $ 19.44万
• 依托单位: RUTGERS, THE STATE UNIV OF N.J.
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-02-14 至 2008-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6844352
• 关键词: behavioral /social science research tag; clinical research; cognitive behavior therapy; comorbidity; congestive heart failure; group counseling; group therapy; human subject; major depression; mental health epidemiology; patient oriented research; psychiatry; psychology; psychotherapy; technology /technique development

DESCRIPTION (provided by applicant): The overall aim of this research is to develop an efficacious group psychotherapy for the treatment of major depression among individuals with congestive heart failure. Both major depression and heart failure are associated with severe loss of functioning and increased mortality, and this co-morbid condition is particularly debilitating. While treating depression among heart failure patients has the potential to improve functioning and prolong life in this population, there are currently no empirically-supported treatments for depression among heart failure patients. Among the several well-validated psychosocial treatments, group cognitive-behavioral therapy (CBT) has been proposed as efficacious, and has established feasibility among heart failure patients. Group CBT may be particularly efficacious among CHF patients with depression due to the potential for increasing patient social support. Initial research suggests that there are several ways in which current group CBT could be improved to treat major depression among CHF patients, including: (1) the use of an "open" group format that allows for immediate patient care, (2) integration of individual interventions to individually tailor treatment goals and improve adherence to treatment, and (3) family-based interventions within the group CBT format to mobilize patient social support. The proposed integrated cognitive-behavioral therapy program includes group, individual, and family treatment (GIFT) for depression among individuals with CHF (GIFT-CHF). The current proposal is designed to develop the GIFT-CHF program. The proposal consists of three phases: a Development, Pilot, and Revision Phase. During the Development phase of the GIFT-CHF, the goal of the research will be to: (a) develop an integrative group therapy program for depressed patients with heart failure (GIFT-CHF); (b) develop a therapist training program; and (c) develop and test the reliability and validity of competence and adherence rating scales. During the Pilot phase of the GIFT-CHF program, the goal will be to conduct a small pilot trial investigating the short-term efficacy of the GIFT-CHF program in comparison to a Standard Medical Care/Wait-List control group, and determine effect size. Finally, during the Revision phase of the GIFT-CHF program, the goal of the research will be based on the results of the Development and Pilot phases, to revise the GIFT-CHF program and treatment manual. This treatment development grant will lay the groundwork for a large-scale treatment outcome study of the GIFT-CHF program for depressed individuals with congestive heart failure.

描述（由申请人提供）：本研究的总体目标是开发一种有效的团体心理疗法，用于治疗充血性心力衰竭患者中的重性抑郁症。重度抑郁症和心力衰竭都与严重的功能丧失和死亡率增加有关，这种合并症尤其使人衰弱。虽然治疗心力衰竭患者中的抑郁症有可能改善这一人群的功能并延长其寿命，但目前尚无心力衰竭患者中抑郁症的药物支持治疗。在几种有效的心理社会治疗方法中，团体认知行为治疗（CBT）被认为是有效的，并在心力衰竭患者中建立了可行性。团体CBT可能是特别有效的CHF患者与抑郁症由于潜在的增加患者的社会支持。初步研究表明，有几种方法可以改善当前的CBT组，以治疗CHF患者中的重度抑郁症，包括：（1）使用“开放”小组形式，允许立即对患者进行护理，（2）整合个体干预以个体定制治疗目标并提高对治疗的依从性，（3）以家庭为基础的干预，以团体CBT的形式动员患者的社会支持。建议的综合认知行为治疗计划包括CHF患者中抑郁症的团体，个人和家庭治疗（GIFT）（GIFT-CHF）。目前的提案旨在制定GIFT-CHF计划。该提案包括三个阶段：开发、试点和修订阶段。在GIFT-CHF的开发阶段，研究的目标是：（a）为心力衰竭抑郁患者（GIFT-CHF）开发一个综合性团体治疗计划;（B）开发一个治疗师培训计划;（c）开发和测试能力和依从性评定量表的信度和效度。在GIFT-CHF项目的试点阶段，目标是进行一项小型试点试验，研究GIFT-CHF项目与标准医疗护理/等待名单对照组相比的短期疗效，并确定效应量。最后，在GIFT-CHF程序的修订阶段，研究的目标将基于开发和试点阶段的结果，修订GIFT-CHF程序和治疗手册。这项治疗开发补助金将为GIFT-CHF项目治疗充血性心力衰竭抑郁症患者的大规模治疗结果研究奠定基础。

项目成果

Integrating co-morbid depression and chronic physical disease management: identifying and resolving failures in self-regulation.

• DOI: 10.1016/j.cpr.2008.09.002
• 发表时间: 2008-12
• 期刊: CLINICAL PSYCHOLOGY REVIEW
• 影响因子: 12.8
• 作者: Detweiler-Bedell, Jerusha B.;Friedman, Michael A.;Leventhal, Howard;Miller, Ivan W.;Leventhal, Elaine A.
• 通讯作者: Leventhal, Elaine A.