Cancer Center Support Grant

癌症中心支持补助金

• 批准号: 8709071
• 负责人: MICHAEL A FRIEDMAN
• 金额: $ 1.07万
• 依托单位: BECKMAN RESEARCH INSTITUTE/CITY OF HOPE
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 2017-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8709071
• 关键词: Animals; Area; Basic Science; Bioinformatics; Biometry; Cancer Center; Cancer Center Support Grant; Cancer Control; Categories; Cities; City of Hope Comprehensive Cancer Center; Clinical; Clinical Data; Clinical Investigator; Clinical Protocols; Clinical Research; Creativeness; Cytometry; Dedications; Development; Diagnostic tests; Disease; Environment; Evaluation; Faculty; Funding; Genomics; Goals; Hematologic Neoplasms; Image; Immunotherapeutic agent; Individual; Institution; Instruction; Intervention; Leadership; Malignant Neoplasms; Medical center; Mission; Pathology; Peer Review; Pharmacology; Population Research; Population Sciences; Recruitment Activity; Request for Applications; Research; Research Infrastructure; Research Institute; Research Personnel; Resource Sharing; Resources; Risk; Scientist; Solid; Source; Structure; Surveys; Technology; Therapeutic; Translations; authority; cancer research center director; cancer therapy; data management; drug discovery; fighting; functional genomics; infrastructure development; innovation; member; molecular oncology; programs; structural biology

DESCRIPTION (provided by applicant): This application seeks renewed CCSG funding for the City of Hope Comprehensive Cancer Center (COHCCC). The COHCCC brings together 131 Members from 34 Departments in the City of Hope Medical Center and the Beckman Research Institute. The Center receives $24,212,096M (Totals) from NCI, $25,947,483M from other peer-reviewed sources, and $31,421,929M from non-peer-reviewed sources, for a total of $81,581,508M in overall funding. Through faculty recruitment, reorganization, and significant infrastructure development, the COHCCC has greatly enhanced its ability to accelerate clinical and translational cancer-focused research. Seventy-two new faculty have been recruited, including 48 clinical investigators and 24 basic and population research scientists. The Cancer Center has five Programs: Molecular Oncology (MONC), Developmental Cancer Therapeutics (DCT), Cancer Immunotherapeutics (CI), Hematologic Malignancies (HM), and Cancer Control and Population Sciences (CCPS). Center membership has been honed to sharpen cancer focus and an Associate Member category has been created for investigators whose potential for peer-reviewed, cancer-focused research is yet developing. This application requests support for ten Shared Resources: Analytical Cytometry, Analytical Pharmacology, Bioinformatics, Functional Genomics/Genomic Sequencing, Pathology, Small Animal Imaging, Drug Discovery and Structural Biology, Survey Research, Biostatistics, and Clinical Protocol and Data Management. The COHCCC is primed to make significant advances in the coming years. Our 72 new basic, population and clinical research recruits will continue to introduce new ideas, technologies, and areas of research focus while enhancing the creative and innovative environment of the Center. Significant infrastructure and other resources have been created to facilitate the translation of discoveries to the rapid development of new cancer treatments, diagnostic tests, and other interventions that would aid people with cancer, as well as individuals at risk for malignancy. Finally, the overall configuration of the institution and its administrative capabilities in terms of leadership, programmatic alignment, development, and authority that have been augmented so that the Cancer Center will be more responsive to its members and to harness their collective energies and creativity. This proposal documents that the COHCCC has built a solid structure for achieving its missions and is stronger and more sustainable than it has ever been.

描述（由申请人提供）：本申请为希望之城综合癌症中心 (COHCCC) 寻求新的 CCSG 资助。 COHCCC 汇集了来自希望之城医疗中心和贝克曼研究所 34 个部门的 131 名成员。该中心从 NCI 获得 24,212,096 百万美元（总计），从其他同行评审来源获得 25,947,483 百万美元，从非同行评审来源获得 31,421,929 百万美元，总资金总额为 81,581,508 万美元。通过教师招聘、重组和重大基础设施开发，COHCCC 大大增强了加速临床和转化癌症研究的能力。已招聘 72 名新教师，其中包括 48 名临床研究人员和 24 名基础和人口研究科学家。癌症中心有五个项目：分子肿瘤学 (MONC)、发育性癌症治疗 (DCT)、癌症免疫治疗 (CI)、血液恶性肿瘤 (HM) 以及癌症控制和人口科学 (CCPS)。中心会员资格经过磨练，以加强对癌症的关注，并为那些尚未开发出同行评审、以癌症为重点的研究潜力的研究人员创建了准会员类别。该应用程序请求支持十个共享资源：分析细胞术、分析药理学、生物信息学、功能基因组学/基因组测序、病理学、小动物成像、药物发现和结构生物学、调查研究、生物统计学以及临床方案和数据管理。 COHCCC 准备在未来几年取得重大进展。我们的 72 名新招募的基础、人口和临床研究人员将继续引入新的想法、技术和研究重点领域，同时增强中心的创造性和创新环境。重要的基础设施和其他资源已经建立，以促进将发现转化为新的癌症治疗、诊断测试和其他干预措施的快速开发，以帮助癌症患者以及面临恶性肿瘤风险的个人。最后，该机构的整体配置及其在领导、计划协调、发展和权威方面的管理能力得到了增强，以便癌症中心能够更好地响应其成员并利用他们的集体能量和创造力。该提案证明 COHCCC 已经为实现其使命建立了坚实的结构，并且比以往任何时候都更强大、更可持续。