Tobacco use in survivors of childhood cancer

描述(由申请人提供)： 由于疾病和治疗，儿科癌症幸存者经历了一系列器官系统随后健康并发症的风险增加。在决定是否从事吸烟等不健康行为时，幸存者应该将他们的医疗脆弱性考虑到他们的决策中。然而，研究表明，儿科癌症幸存者经常从事不健康行为的比率与他们的健康同龄人相似，尽管幸存者对器官毒性的易感性增加。因此，需要计划来帮助幸存者对他们的健康行为做出知情的、健康的决定，以努力延长他们的无病状态。鉴于吸烟和有问题的健康后果之间的已知联系，烟草使用是干预的一个重要重点。为了向预防工作提供信息，有必要更好地了解哪些因素影响幸存者关于吸烟的决定，并在幸存者独特的医疗背景下考虑这些因素。这项建议的目的是：1)评估青少年癌症幸存者的烟草使用情况；2)确定这一人群中与烟草使用有关的风险因素；3)确定某些幸存者群体在决定使用烟草时是否更容易受到外部影响。这项研究将描述与青少年幸存者使用烟草有关的生物、心理和社会变量，以指导未来更大规模的调查和预防工作。

DESCRIPTION (provided by applicant): Resulting from disease and treatment, pediatric cancer survivors experience an increased risk of subsequent health complications across a range of organ systems. When deciding whether to engage in unhealthy behaviors, such as smoking, survivors should factor their medical vulnerability into their decision-making. However, research has demonstrated that pediatric cancer survivors often engage in unhealthy behaviors at rates similar to their healthy peers, despite survivors having an increased vulnerability to organ toxicity. Thus, programs are needed to help survivors make informed, healthy decisions about their health behaviors in an effort to prolong their disease-free status. Tobacco use is an important focus for intervention, given the known connections between smoking and problematic health consequences. In order to inform prevention efforts, it is necessary to better understand what factors influence survivors in their decisions about smoking and to consider these factors within the context of survivors' unique medical context. The objectives of this proposal are: 1) to assess the prevalence of tobacco use in adolescent survivors of pediatric cancer, 2) to determine risk factors associated with tobacco use in this population, and 3) to ascertain if certain groups of survivors are more vulnerable to external influences when deciding to use tobacco. This research will describe biological, psychological, and social variables that are associated with tobacco use in adolescent survivors in order to direct larger investigations and prevention efforts in the future.