Neural Mechanisms of Planning and Control of Movement
运动规划和控制的神经机制
基本信息
- 批准号:6844768
- 负责人:
- 金额:$ 17.53万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2002
- 资助国家:美国
- 起止时间:2002-01-01 至 2007-12-31
- 项目状态:已结题
- 来源:
- 关键词:Macaca mulattabehavioral /social science research tagbiological signal transductioncueselectromyographylimb movementmotor cortexneural information processingneuromuscular functionneurophysiologyneuropsychological testsparietal lobe /cortexpsychomotor functionsensorimotor systemstatistics /biometryvisual stimulusvisual tracking
项目摘要
DESCRIPTION:(provided by applicant)
The long term goal of this research is to elucidate how the brain specifies
movement parameters before the initiation of a motor response, transforms these
parameters when needed, and monitors them during the execution of a movement.
These processes are incessantly used in the behavioral repertoire of many
animal species, for example in activities as diverse as hunting preys or
playing tennis. However, little attention has been given so far to the
neurophysiological mechanisms associated with the amendment of movement
parameters. The activity of neurons from cortical areas related to the
preparation and execution of arm movements will be recorded in rhesus monkeys
while they perform in specific tasks. These areas include the primary motor
cortex, the dorsal premotor cortex and the posterior parietal cortex, which are
considered essential nodes in the neural network engaged in planning and
executing movements. A series of tasks was planned to investigate the neural
processes associated with specifying movement parameters, and the
transformation of this representation as needed in response to changes in the
environment. A first group of tasks requires either discrete pointing arm
movements toward a visual target that switches position, or continuous tracking
of a moving target that moves first in one direction and then suddenly changes
direction. In both cases the visually specified direction of movement is
modified at some point either before or during the movement and requires a
corresponding change in the specification of the motor response. The tasks are
designed to characterize the patterns of neuronal activity engaged in defining
and updating the visually specified goal of the motor output. In the first two
tasks mentioned above, only one visual stimulus is present at any time before
or during the motor response, and therefore the aim of the response is always
unambiguously defined. However, it is also common that multiple alternatives
for the upcoming motor response are considered before one is actually selected
and executed. For example, while hunting it may be expected that the prey is
more likely to escape in some directions than others, or while playing tennis
that the opponent player responds by sending the ball at some angles rather
than others. The neural process of preparatory activity will be investigated by
using a precuing paradigm: two stimuli indicating two alternative possible
responses are displayed, and after a delay one of them will become the actual
target The analysis of the neural activity will address the questions of what
are the characteristics of the preparatory activity, in particular in relation
with the degree of disparity between the alternative responses; and how is this
activity transformed when one of the alternative motor responses is selected.
In all the experiments planned, the neuronal activity will be investigated both
at the single-cell and population level. The analysis will serve to
characterize the dynamics of the neural representation of movement parameters,
in particular direction and amplitude, while it is formed before the initiation
of the movement, and while it is transformed in response to the requirements of
the task.
描述:(由申请人提供)
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('GIUSEPPE PELLIZZER', 18)}}的其他基金
Multidimensional Evaluation of Neural Dynamics in Patients with Disorders of Consciousness using EEG
使用脑电图对意识障碍患者的神经动力学进行多维评估
- 批准号:
10359670 - 财政年份:2019
- 资助金额:
$ 17.53万 - 项目类别:
Multidimensional Evaluation of Neural Dynamics in Patients with Disorders of Consciousness using EEG
使用脑电图对意识障碍患者的神经动力学进行多维评估
- 批准号:
9910073 - 财政年份:2019
- 资助金额:
$ 17.53万 - 项目类别:
Neural Mechanisms of Planning and Control of Movement
运动规划和控制的神经机制
- 批准号:
6621614 - 财政年份:2002
- 资助金额:
$ 17.53万 - 项目类别:
Neural Mechanisms of Planning and Control of Movement
运动规划和控制的神经机制
- 批准号:
6435347 - 财政年份:2002
- 资助金额:
$ 17.53万 - 项目类别:
Neural Mechanisms of Planning and Control of Movement
运动规划和控制的神经机制
- 批准号:
6693011 - 财政年份:2002
- 资助金额:
$ 17.53万 - 项目类别: