Mechanisms and Effects of Chiropractic Manipulation

帕尔默捏脊研究中心（PCCR）提议建立一个为期3年的多学科发展中心，研究捏脊手法的机制和效果，以提高正在进行的研究项目的水平和质量，推进科学专业知识和研究基础设施，并支持加强帕尔默捏脊大学、爱荷华大学、堪萨斯州立大学、加州大学和加州大学的12名研究人员之间的沟通和合作。纽约州立大学和国立健康科学大学。中心将开展4个协同研究项目。中心的中心科学主题是

Palmer Center for Chiropractic Research (PCCR) proposes to establish a 3 year multidisciplinary Developmental Center for the Study of Mechanisms and Effects of Chiropractic Manipulation (Center) to increase the level and quality of the ongoing research program, to advance scientific expertise and research infrastructure, and to support enhanced communication and partnering among 12 investigators at Palmer Chiropractic University, the University of Iowa, Kansas State University, State University of New York, and National University of Health Sciences. The Center will facilitate 4 synergistic research projects. The central scientific theme of the Center is focused on spinal manipulation (SM), low back pain (LBP), and the mechanisms of action of SM. The long range goal is to explore and understand the clinical role of SM and the physiological and biomechanical mechanisms of SM loads. Project 1 will study the biomechanical and neurological effects of vertebral loading on the facet joint capsule using an animal model. Project 2 will study the behavioral, biomechanical and biological effects of SM in a rat spine fixation model. Project 3 will explore variables that predict an important clinical effect of SM in patients with LBP, examine changes in biomechanical and physiological functions of patients undergoing SM, and biomechanically characterize 2 forms of SM. Project 4 will study the effect of vertebral loading on sympathetic nerve regulation in an animal model. Projects will be supported by the Data Management and Biostatistics Core, the Biomechanics Core and the Administration Core. Investigators will use pilot data to submit competitive grant applications to NIH, and will provide research training experiences for future CAM investigators. The developmental Center will build on and extend the successful recent history of the NIH supported, Consortial Center for Chiropractic Research at PCCR. It will provide the focus and direction to synergistically increase the "critical mass" of personnel and resources to address an important unmet public health need.